Potential Use of Essential Oil Isolated from Cleistocalyx operculatus Leaves as a Topical Dermatological Agent for Treatment of Burn Wound
Joint Authors
Tran, Gia-Buu
Le, Nghia-Thu Tram
Dam, Sao-Mai
Source
Dermatology Research and Practice
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-03-05
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Several herbal remedies have been used as topical agents to cure burn wound, one of the most common injuries in worldwide.
In this study, we investigated the potential use of Cleistocalyx operculatus essential oil to treat the burn wound.
We identified a total of 13 bioactive compounds of essential oil, several of which exhibited the anti-inflammatory and antimicrobial activities.
Furthermore, the essential oil showed the antibacterial effect against S.
aureus but not with P.
aeruginosa.
The supportive effect of essential oil on burn wound healing process also has been proven.
Among three groups of mice, wound contraction rate of essential oil treated group (100%) was significantly higher than tamanu oil treated (79%) and control mice (71%) after 20 days (0.22±0.03 versus 0.31±0.02 cm2, resp., p<0.05).
Histological studies revealed that burn wounds treated with essential oil formed a complete epidermal structure, thick and neatly arranged fibers, and scattered immune cells in burn wound.
On the contrary, saline treated burn wound formed uneven epidermal layer with necrotic ulcer, infiltration of immune cells, and existence of granulation tissue.
This finding demonstrated Cleistocalyx operculatus essential oil as promising topical dermatological agent to treat burn wound.
American Psychological Association (APA)
Tran, Gia-Buu& Le, Nghia-Thu Tram& Dam, Sao-Mai. 2018. Potential Use of Essential Oil Isolated from Cleistocalyx operculatus Leaves as a Topical Dermatological Agent for Treatment of Burn Wound. Dermatology Research and Practice،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1153844
Modern Language Association (MLA)
Tran, Gia-Buu…[et al.]. Potential Use of Essential Oil Isolated from Cleistocalyx operculatus Leaves as a Topical Dermatological Agent for Treatment of Burn Wound. Dermatology Research and Practice No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1153844
American Medical Association (AMA)
Tran, Gia-Buu& Le, Nghia-Thu Tram& Dam, Sao-Mai. Potential Use of Essential Oil Isolated from Cleistocalyx operculatus Leaves as a Topical Dermatological Agent for Treatment of Burn Wound. Dermatology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1153844
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153844