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In Vitro Control of Uropathogenic Microorganisms with the Ethanolic Extract from the Leaves of Cochlospermum regium (Schrank) Pilger
Joint Authors
Svidzinski, Terezinha Inez Estivalet
Negri, Melyssa
Mota, Jonas da Silva
Cardoso, Claudia Andréa Lima
Leme, Danny Ellen Meireles
Rodrigues, Allan Belarmino
Almeida-Apolonio, Adriana Araújo de
Dantas, Fabiana Gomes da Silva
Oliveira, Kelly Mari Pires de
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-11
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The roots of Cochlospermum regium, popularly known as “algodãozinho-do-cerrado,” are used for the treatment of genitourinary infections.
However, the removal of their subterranean structures results in the death of the plant, and the use of the leaves becomes a viable alternative.
Therefore, the antimicrobial activity of Cochlospermum regium leaf’s ethanolic extract and its action on the biofilm formation of microorganisms associated with urinary infection were evaluated.
The total phenolic compounds, flavoids, and tannins were quantified using the reagents Folin-Ciocalteu, aluminum chloride, and vanillin, respectively.
The antimicrobial activity was evaluated by the broth microdilution method and the effect of the extract in the biofilm treatment was measured by the drop plate method.
Cytotoxicity was evaluated by the method based on the reduction of MTS and the mutagenicity by the Ames test.
The ethanolic extract of C.
regium leaves presented 87.4 mg/EQ of flavonoids, 167.2 mg/EAG of total phenolic compounds, and 21.7 mg/ECA of condensed tannins.
It presented reduction of the biofilm formation for E.
coli and C.
tropicalis and antimicrobial action of 1 mg/mL and 0.5 mg/mL, respectively.
The extract showed no cytotoxicity and mutagenicity at the concentrations tested.
This study demonstrated that C.
regium leaves are a viable option for the treatment of genitourinary infections and for the species preservation.
American Psychological Association (APA)
Leme, Danny Ellen Meireles& Rodrigues, Allan Belarmino& Almeida-Apolonio, Adriana Araújo de& Dantas, Fabiana Gomes da Silva& Negri, Melyssa& Svidzinski, Terezinha Inez Estivalet…[et al.]. 2017. In Vitro Control of Uropathogenic Microorganisms with the Ethanolic Extract from the Leaves of Cochlospermum regium (Schrank) Pilger. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1153845
Modern Language Association (MLA)
Leme, Danny Ellen Meireles…[et al.]. In Vitro Control of Uropathogenic Microorganisms with the Ethanolic Extract from the Leaves of Cochlospermum regium (Schrank) Pilger. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1153845
American Medical Association (AMA)
Leme, Danny Ellen Meireles& Rodrigues, Allan Belarmino& Almeida-Apolonio, Adriana Araújo de& Dantas, Fabiana Gomes da Silva& Negri, Melyssa& Svidzinski, Terezinha Inez Estivalet…[et al.]. In Vitro Control of Uropathogenic Microorganisms with the Ethanolic Extract from the Leaves of Cochlospermum regium (Schrank) Pilger. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1153845
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153845