Autologous Fat Grafting in the Treatment of Facial Scleroderma
Joint Authors
Mozafari, Nikoo
Ahmadzadeh, Arman
Gheisari, Mehdi
Nobari, Nilofar
Iranmanesh, Behzad
Source
Dermatology Research and Practice
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-08-01
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Systemic sclerosis (SSc) is a rare systemic autoimmune disease, characterized by progressive cutaneous and internal organ fibrosis.
Orofacial manifestations of systemic sclerosis are extremely disabling and treatment options are limited.
In this study, we aimed to assess the safety and efficacy of autologous fat grafting in the face of patients with systemic sclerosis.
We enrolled 16 SSc patients suffering from facial sclerosis and limited mouth opening capacity.
Autologous fat injection ranging from 15 to 40 ml was administered per patient, based on their face morphology.
The patients were evaluated at baseline and 3 months after fat injection.
Evaluations included mouth opening capacity, mouth handicap in systemic sclerosis (MHISS), Rodnan skin sclerosis score, skin biophysical properties using a sensitive biometrologic device with the assessment of cutaneous resonance running time (CRRT), volumizing and aesthetic effects based on pre- and posttreatment photographs, possible side effects, and global patient satisfaction.
Clinical assessment showed autologous fat transfer significantly improved mouth opening capacity and the MHISS and Rodnan score of patients with facial scleroderma (p value <.001).
The aesthetic and/or functional results of fat injection were satisfying to about 80% of the patients.
The changes in CRRT values were not significant.
Our findings support the possible therapeutic role of autologous fat grafting in improving facial scleroderma both in aesthetic and in functional aspects.
This trial is registered with IRCT20180209038677N1.
American Psychological Association (APA)
Gheisari, Mehdi& Ahmadzadeh, Arman& Nobari, Nilofar& Iranmanesh, Behzad& Mozafari, Nikoo. 2018. Autologous Fat Grafting in the Treatment of Facial Scleroderma. Dermatology Research and Practice،Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1153884
Modern Language Association (MLA)
Gheisari, Mehdi…[et al.]. Autologous Fat Grafting in the Treatment of Facial Scleroderma. Dermatology Research and Practice No. 2018 (2018), pp.1-7.
https://search.emarefa.net/detail/BIM-1153884
American Medical Association (AMA)
Gheisari, Mehdi& Ahmadzadeh, Arman& Nobari, Nilofar& Iranmanesh, Behzad& Mozafari, Nikoo. Autologous Fat Grafting in the Treatment of Facial Scleroderma. Dermatology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-7.
https://search.emarefa.net/detail/BIM-1153884
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153884