Compound Danshen Dripping Pill for Treating Nonproliferative Diabetic Retinopathy: A Meta-Analysis of 13 Randomized Controlled Trials
Joint Authors
Lian, Fengmei
Jin, De
Bao, Qi
Huang, Wenjing
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-24
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Objective.
We assess the clinical effect of compound Danshen dripping pill (CDDP) for treating diabetic retinopathy (DR).
Methods.
Electronic databases were searched from January 2001 to October 2016 to locate randomized controlled trials (RCTs).
Efficacy was measured as main outcome and microaneurysms, hemorrhage, exudate, vision, and fundus fluorescein angiography (FFA) were measured as second outcomes.
Methodological quality for each study was evaluated, RevMan 5 software was used to assess treatment effects, and GRADE was used to rate quality of evidence.
Results.
We located 13 RCTs and methodological quality was evaluated as high risk.
Statistics indicated CDDP for treating DR was better than controls and DR risk was reduced 64% with CDDP (RR: 0.36, P=0.68); retinal microaneurysms (MD = −4.32NO, P<0.00001); retinal hemorrhages (MD = −0.70PD, P=0.03); exudate improvements (MD = −0.09PD, P=0.79); visual changes (MD = −0.12 letter, P=0.006); FFA (RR: 0.40, P=0.003).
About GRADE, quality of evidence was “low.” Conclusion.
CDDP may be safe and efficacious for treating or delaying DR and may improve vision or delay vision loss.
American Psychological Association (APA)
Huang, Wenjing& Bao, Qi& Jin, De& Lian, Fengmei. 2017. Compound Danshen Dripping Pill for Treating Nonproliferative Diabetic Retinopathy: A Meta-Analysis of 13 Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1153897
Modern Language Association (MLA)
Huang, Wenjing…[et al.]. Compound Danshen Dripping Pill for Treating Nonproliferative Diabetic Retinopathy: A Meta-Analysis of 13 Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1153897
American Medical Association (AMA)
Huang, Wenjing& Bao, Qi& Jin, De& Lian, Fengmei. Compound Danshen Dripping Pill for Treating Nonproliferative Diabetic Retinopathy: A Meta-Analysis of 13 Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1153897
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153897