Clinical Predictive Factors of Lower Extremity Deep Vein Thrombosis in Relative High-Risk Patients after Neurosurgery: A Retrospective Study
Joint Authors
Zhu, Xiaole
Li, Juhua
Ren, XinZhen
Chen, Huayu
Lin, Zhen
Huang, Mei
Gu, Zejuan
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-06
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Introduction.
It is acknowledged that patients undergoing neurosurgery with neurological illness are at higher risk of lower extremity deep vein thrombosis (DVT).
As an underlying life-threatening complication, the incidence and risk factors for high-risk patients with lower extremity deep vein thrombosis are still controversial in relative high-risk patients after neurosurgery.
Materials and Methods.
A total of 204 patients who underwent neurosurgery and were considered as a high-risk group of DVT according to times of stay in bed more than 3 days were enrolled in this study.
We evaluated the lower extremity DVT by using Color Doppler Ultrasound System (CDUS).
Clinical parameters of patients at the time of admission and postoperation were recorded and prepared for further analysis.
Early predictive factors for postoperative lower extremity DVT were established.
Diagnostic performance of predictive factors was evaluated by using receiver operating characteristic (ROC) curve analysis.
Results.
The overall incidence rate of DVT in 204 enrolled patients was 30.9%.
Multivariate logistic regression indicated that hypertension (OR 3.159, 95% CI 1.465-6.816; P=0.003), higher postoperative D-dimer (OR 1.225, 95% CI 1.016-1.477; P=0.034), female (OR 0.174, 95% CI 0.054-0.568; P=0.004), and lower GCS score (OR 0.809, 95% CI 0.679-0.965; P=0.013) were independently associated with incidence of DVT in patients after neurosurgery.
The logistic regression function (LR model) of these four independent risk factors had a better performance on diagnostic value of DVT in patients after neurosurgery.
Conclusion.
The combined factor was constructed by hypertension, postoperative D-dimer, gender, and GCS score, and it might be a more handy and reliable marker to stratify patients at risk of DVT after neurosurgery.
American Psychological Association (APA)
Li, Juhua& Ren, XinZhen& Zhu, Xiaole& Chen, Huayu& Lin, Zhen& Huang, Mei…[et al.]. 2020. Clinical Predictive Factors of Lower Extremity Deep Vein Thrombosis in Relative High-Risk Patients after Neurosurgery: A Retrospective Study. Disease Markers،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1153900
Modern Language Association (MLA)
Li, Juhua…[et al.]. Clinical Predictive Factors of Lower Extremity Deep Vein Thrombosis in Relative High-Risk Patients after Neurosurgery: A Retrospective Study. Disease Markers No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1153900
American Medical Association (AMA)
Li, Juhua& Ren, XinZhen& Zhu, Xiaole& Chen, Huayu& Lin, Zhen& Huang, Mei…[et al.]. Clinical Predictive Factors of Lower Extremity Deep Vein Thrombosis in Relative High-Risk Patients after Neurosurgery: A Retrospective Study. Disease Markers. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1153900
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153900