Immunoregulation of Shenqi Fuzheng Injection Combined with Chemotherapy in Cancer Patients: A Systematic Review and Meta-Analysis
Joint Authors
Zhang, Boli
Fu, Shufei
Gao, Xiu-Mei
Wang, Xiaoying
Tan, Wangxiao
Liu, Xiao
Yang, Yang
Ting, Wang
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-16, 16 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-05
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Abstract EN
Background.
Immunosuppression is a well-recognised complication of chemotherapy in cancer patients.
We assemble the clinical evidence that SQI, an adjuvant drug for lung cancer and gastric cancer which was widely prescribed in China, interventions could increase objective tumour response and regulate immunity in cancer patients undergoing chemotherapy.
Methods.
We undertook a systemic review of the clinical data from randomised controlled trials up to September 2015 in which a SQI intervention was compared with a control arm in patients undergoing conventional chemotherapy.
Revman 5.0 Software was used for the data analysis.
Results.
49 randomised controlled trials were included in the systematic review.
The meta-analysis results demonstrated that the SQI intervention with conventional chemotherapy exhibited better therapeutic efficacy than the conventional chemotherapy group with a statistically significant higher objective tumour response.
Cotreatment with SQI could enhance NK, CD3+, CD4+ level, and CD4+/CD8+ ratio comparing with the conventional chemotherapy group.
Conclusions.
The conclusions of this review might suggest a high risk of bias due to the low quality and the limitation of cancer types in the included trials.
A more reliable conclusion regarding the immunoregulation of SQI could be reached based on more trials of higher quality.
American Psychological Association (APA)
Yang, Yang& Ting, Wang& Liu, Xiao& Fu, Shufei& Tan, Wangxiao& Wang, Xiaoying…[et al.]. 2017. Immunoregulation of Shenqi Fuzheng Injection Combined with Chemotherapy in Cancer Patients: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-16.
https://search.emarefa.net/detail/BIM-1153954
Modern Language Association (MLA)
Yang, Yang…[et al.]. Immunoregulation of Shenqi Fuzheng Injection Combined with Chemotherapy in Cancer Patients: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-16.
https://search.emarefa.net/detail/BIM-1153954
American Medical Association (AMA)
Yang, Yang& Ting, Wang& Liu, Xiao& Fu, Shufei& Tan, Wangxiao& Wang, Xiaoying…[et al.]. Immunoregulation of Shenqi Fuzheng Injection Combined with Chemotherapy in Cancer Patients: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-16.
https://search.emarefa.net/detail/BIM-1153954
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153954