Antibiofilm and Antioxidant Activity of Propolis and Bud Poplar Resins versus Pseudomonas aeruginosa
Joint Authors
De Marco, Stefania
Piccioni, Miranda
Pagiotti, Rita
Pietrella, Donatella
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-03
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Pseudomonas aeruginosa is a common biofilm-forming bacterial pathogen implicated in lung, skin, and systemic infections.
Biofilms are majorly associated with chronic lung infection, which is the most severe complication in cystic fibrosis patients characterized by drug-resistant biofilms in the bronchial mucus with zones, where reactive oxygen species concentration is increased mainly due to neutrophil activity.
Aim of this work is to verify the anti-Pseudomonas property of propolis or bud poplar resins extracts.
The antimicrobial activity of propolis and bud poplar resins extracts was determined by MIC and biofilm quantification.
Moreover, we tested the antioxidant activity by DPPH and neutrophil oxidative burst assays.
In the end, both propolis and bud poplar resins extracts were able to inhibit P.
aeruginosa biofilm formation and to influence both swimming and swarming motility.
Moreover, the extracts could inhibit proinflammatory cytokine production by human PBMC and showed both direct and indirect antioxidant activity.
This work is the first to demonstrate that propolis and bud poplar resins extracts can influence biofilm formation of P.
aeruginosa contrasting the inflammation and the oxidation state typical of chronic infection suggesting that propolis or bud poplar resins can be used along with antibiotic as adjuvant in the therapy against P.
aeruginosa infections related to biofilm.
American Psychological Association (APA)
De Marco, Stefania& Piccioni, Miranda& Pagiotti, Rita& Pietrella, Donatella. 2017. Antibiofilm and Antioxidant Activity of Propolis and Bud Poplar Resins versus Pseudomonas aeruginosa. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1153993
Modern Language Association (MLA)
De Marco, Stefania…[et al.]. Antibiofilm and Antioxidant Activity of Propolis and Bud Poplar Resins versus Pseudomonas aeruginosa. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1153993
American Medical Association (AMA)
De Marco, Stefania& Piccioni, Miranda& Pagiotti, Rita& Pietrella, Donatella. Antibiofilm and Antioxidant Activity of Propolis and Bud Poplar Resins versus Pseudomonas aeruginosa. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1153993
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1153993