High JAK2 Protein Expression Predicts a Poor Prognosis in Patients with Resectable Pancreatic Ductal Adenocarcinoma
Joint Authors
Wang, Zhe
Song, Yang
Tang, Mei-Yue
Wang, Si-Liang
Chen, Wei
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-22
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
Pancreatic ductal adenocarcinoma (PDAC) is one of the most fatal malignancies worldwide.
The JAK/STAT signaling pathway is involved in pancreatic cancer tumorigenesis.
However, the prognostic value of JAK2 expression in resectable PDAC is unclear.
Method.
In this study, we performed a clinicopathological analysis of 62 resectable PDAC cases with a primary focus on survival.
JAK2 expression was examined by immunohistochemistry.
The relationship between JAK2 expression and clinicopathological features and prognosis was analyzed.
Results.
Survival curve analyses revealed that high levels of JAK2 expression predict a poor prognosis in resectable PDAC patients.
Multivariate analysis confirmed that JAK2 expression can predict the prognosis of PDAC.
Conclusions.
Assessment of JAK2 protein expression may be a promising method to predict prognosis in patients with resectable PDAC.
American Psychological Association (APA)
Song, Yang& Tang, Mei-Yue& Chen, Wei& Wang, Zhe& Wang, Si-Liang. 2020. High JAK2 Protein Expression Predicts a Poor Prognosis in Patients with Resectable Pancreatic Ductal Adenocarcinoma. Disease Markers،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1154008
Modern Language Association (MLA)
Song, Yang…[et al.]. High JAK2 Protein Expression Predicts a Poor Prognosis in Patients with Resectable Pancreatic Ductal Adenocarcinoma. Disease Markers No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1154008
American Medical Association (AMA)
Song, Yang& Tang, Mei-Yue& Chen, Wei& Wang, Zhe& Wang, Si-Liang. High JAK2 Protein Expression Predicts a Poor Prognosis in Patients with Resectable Pancreatic Ductal Adenocarcinoma. Disease Markers. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1154008
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154008