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A Pilot Randomized, Controlled Study of Nanocrystalline Silver, Manuka Honey, and Conventional Dressing in Healing Diabetic Foot Ulcer
Joint Authors
Tsang, Ka-Kit
To, Tony Shing-Shun
Wong, Thomas Kwok-Shing
Kwong, Enid Wai-Yung
Chung, Joanne W. Y.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-25
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Nanocrystalline silver (nAg) and Manuka honey (MH) dressing have increasing popularity for treating diabetic foot ulcer (DFU).
This study was an open-label randomized controlled trial with three parallel groups’ design in examining the preliminary effectiveness of nAg against MH and conventional dressing in healing DFU in terms of ulcer healing, ulcer infection, and inflammation.
31 participants (11 in the nAg group, 10 in the MH group, and 10 in the convention group) diagnosed with type 2 diabetes were enrolled.
Wound cleaning, debridement, and topical dressing application were performed according to the group allocation in each visit at weeks 1, 2, 3, 4, 6, 8, 10, and 12.
The results found that the proportions of complete ulcer healing were 81.8%, 50%, and 40% in the nAg, MH, and conventional groups, respectively.
The ulcer size reduction rate was potentially higher in the nAg group (97.45%) than the MH group (86.21%) and the conventional group (75.17%).
In bacteriology, nAg showed a greater rate of microorganism reduction although it was not significant.
To conclude, nAg alginate was potentially superior to MH and conventional dressing in healing diabetic foot ulcer in terms of ulcer size reduction rate.
American Psychological Association (APA)
Tsang, Ka-Kit& Kwong, Enid Wai-Yung& To, Tony Shing-Shun& Chung, Joanne W. Y.& Wong, Thomas Kwok-Shing. 2017. A Pilot Randomized, Controlled Study of Nanocrystalline Silver, Manuka Honey, and Conventional Dressing in Healing Diabetic Foot Ulcer. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-15.
https://search.emarefa.net/detail/BIM-1154032
Modern Language Association (MLA)
Tsang, Ka-Kit…[et al.]. A Pilot Randomized, Controlled Study of Nanocrystalline Silver, Manuka Honey, and Conventional Dressing in Healing Diabetic Foot Ulcer. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-15.
https://search.emarefa.net/detail/BIM-1154032
American Medical Association (AMA)
Tsang, Ka-Kit& Kwong, Enid Wai-Yung& To, Tony Shing-Shun& Chung, Joanne W. Y.& Wong, Thomas Kwok-Shing. A Pilot Randomized, Controlled Study of Nanocrystalline Silver, Manuka Honey, and Conventional Dressing in Healing Diabetic Foot Ulcer. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-15.
https://search.emarefa.net/detail/BIM-1154032
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154032