Medicinal Plants for the Treatment of Local Tissue Damage Induced by Snake Venoms: An Overview from Traditional Use to Pharmacological Evidence
Joint Authors
Zucolotto, Silvana Maria
Félix-Silva, Juliana
Fernandes-Pedrosa, Matheus de Freitas
Silva-Júnior, Arnóbio Antônio da
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-52, 52 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-21
Country of Publication
Egypt
No. of Pages
52
Main Subjects
Abstract EN
Snakebites are a serious problem in public health due to their high morbimortality.
Most of snake venoms produce intense local tissue damage, which could lead to temporary or permanent disability in victims.
The available specific treatment is the antivenom serum therapy, whose effectiveness is reduced against these effects.
Thus, the search for complementary alternatives for snakebite treatment is relevant.
There are several reports of the popular use of medicinal plants against snakebites worldwide.
In recent years, many studies have been published giving pharmacological evidence of benefits of several vegetal species against local effects induced by a broad range of snake venoms, including inhibitory potential against hyaluronidase, phospholipase, proteolytic, hemorrhagic, myotoxic, and edematogenic activities.
In this context, this review aimed to provide an updated overview of medicinal plants used popularly as antiophidic agents and discuss the main species with pharmacological studies supporting the uses, with emphasis on plants inhibiting local effects of snake envenomation.
The present review provides an updated scenario and insights into future research aiming at validation of medicinal plants as antiophidic agents and strengthens the potentiality of ethnopharmacology as a tool for design of potent inhibitors and/or development of herbal medicines against venom toxins, especially local tissue damage.
American Psychological Association (APA)
Félix-Silva, Juliana& Silva-Júnior, Arnóbio Antônio da& Zucolotto, Silvana Maria& Fernandes-Pedrosa, Matheus de Freitas. 2017. Medicinal Plants for the Treatment of Local Tissue Damage Induced by Snake Venoms: An Overview from Traditional Use to Pharmacological Evidence. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-52.
https://search.emarefa.net/detail/BIM-1154104
Modern Language Association (MLA)
Félix-Silva, Juliana…[et al.]. Medicinal Plants for the Treatment of Local Tissue Damage Induced by Snake Venoms: An Overview from Traditional Use to Pharmacological Evidence. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-52.
https://search.emarefa.net/detail/BIM-1154104
American Medical Association (AMA)
Félix-Silva, Juliana& Silva-Júnior, Arnóbio Antônio da& Zucolotto, Silvana Maria& Fernandes-Pedrosa, Matheus de Freitas. Medicinal Plants for the Treatment of Local Tissue Damage Induced by Snake Venoms: An Overview from Traditional Use to Pharmacological Evidence. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-52.
https://search.emarefa.net/detail/BIM-1154104
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154104