Prognostic Value of Microvessel Density in Head and Neck Squamous Cell Carcinoma: A Meta-Analysis
Joint Authors
Ma, Guangzhi
Liu, Yukun
Dong, Yanbo
Lu, Siyu
Liu, Liangfa
Source
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-28
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
The prognostic value of microvessel density (MVD) in head and neck squamous cell carcinoma (HNSCC) remains disputable.
The purpose of this study was to comprehensively determine the prognostic value of MVD in HNSCC.
Relevant literatures were identified using PubMed, Embase, and Cochrane Library.
A meta-analysis was performed to clarify the prognostic role of MVD in HNSCC patients and different subgroups.
A total of 14 eligible articles were included in this meta-analysis.
The combined hazard ratio (HR) and 95% confidence interval (95% CI) for overall survival (OS) of 11 studies was 1.663 (1.236-2.237, P=0.001), and the pooled HR and 95% CI for progression-free survival (PFS) of 7 studies was 2.069 (1.281-3.343, P=0.003).
Subgroup analyses were also performed on different issues, such as regional distribution of patients, age, tumor location, antibody, and treatment strategy.
To conclude, high MVD is associated with worse OS and PFS in patients with HNSCC.
American Psychological Association (APA)
Dong, Yanbo& Ma, Guangzhi& Liu, Yukun& Lu, Siyu& Liu, Liangfa. 2020. Prognostic Value of Microvessel Density in Head and Neck Squamous Cell Carcinoma: A Meta-Analysis. Disease Markers،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1154111
Modern Language Association (MLA)
Dong, Yanbo…[et al.]. Prognostic Value of Microvessel Density in Head and Neck Squamous Cell Carcinoma: A Meta-Analysis. Disease Markers No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1154111
American Medical Association (AMA)
Dong, Yanbo& Ma, Guangzhi& Liu, Yukun& Lu, Siyu& Liu, Liangfa. Prognostic Value of Microvessel Density in Head and Neck Squamous Cell Carcinoma: A Meta-Analysis. Disease Markers. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1154111
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154111