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Bletilla striata Micron Particles Function as a Hemostatic Agent by Promoting Rapid Blood Aggregation
Joint Authors
Zhang, Chen
Zeng, Rui
Liao, Zhencheng
Fu, Chaomei
Luo, Hui
Qu, Yan
Yang, Han-shuo
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-12
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The human body cannot control blood loss without treatment.
Available hemostatic agents are ineffective at treating cases of severe bleeding and are expensive or raise safety concerns.
Bletilla striata serve as an inexpensive, natural, and promising alternative.
However, no detailed studies on its hemostatic approach have been performed.
The aim of this study was to examine the hemostatic effects of B.
striata Micron Particles (BSMPs) and their hemostatic mechanisms.
We prepared and characterized BSMPs of different size ranges and investigated their use as hemostatic agent.
BSMPs of different size ranges were characterized by scanning electron microscope.
In vitro coagulation studies revealed BSMP-blood aggregate formation via stereoscope and texture analyzers.
In vivo studies based on rat injury model illustrated the BSMP capabilities under conditions of hemostasis.
Compared to other BSMPs of different size ranges, BSMPs of 350–250 μm are most efficient in hemostasis.
As powder sizes decrease, the degree of aggregation between particles and hemostatic BSMP effects declines.
The BSMP in contact with a bleeding surface locally forms a visible particle/blood aggregate as a physical barrier that facilitates hemostasis.
Considering the facile preparation, low cost, and long shelf life of B.
striata, BSMPs offer great potential as mechanisms of trauma treatment.
American Psychological Association (APA)
Zhang, Chen& Zeng, Rui& Liao, Zhencheng& Fu, Chaomei& Luo, Hui& Yang, Han-shuo…[et al.]. 2017. Bletilla striata Micron Particles Function as a Hemostatic Agent by Promoting Rapid Blood Aggregation. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1154129
Modern Language Association (MLA)
Zhang, Chen…[et al.]. Bletilla striata Micron Particles Function as a Hemostatic Agent by Promoting Rapid Blood Aggregation. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1154129
American Medical Association (AMA)
Zhang, Chen& Zeng, Rui& Liao, Zhencheng& Fu, Chaomei& Luo, Hui& Yang, Han-shuo…[et al.]. Bletilla striata Micron Particles Function as a Hemostatic Agent by Promoting Rapid Blood Aggregation. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1154129
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154129