The Effects of Modified Simiao Decoction in the Treatment of Gouty Arthritis: A Systematic Review and Meta-Analysis
Joint Authors
Liu, Yafei
Chen, Zhe
Wen, Cai-Yu-Zhu
Huang, Ying
Zhang, Jun-Jun
Xing, Guo-Lan
Tu, Shenghao
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-08
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
The modified Simiao decoctions (MSD) have been wildly applied in the treatment of gouty arthritis in China.
However, the evidence needs to be evaluated by a systematic review and meta-analysis.
After filtering, twenty-four randomised, controlled trials (RCTs) comparing the effects of MSD and anti-inflammation medications and/or urate-lowering therapies in patients with gouty arthritis were included.
In comparison with anti-inflammation medications, urate-lowering therapies, or coadministration of anti-inflammation medications and urate-lowering therapies, MSD monotherapy significantly lowered serum uric acid (p<0.00001, mean difference = −90.62, and 95% CI [−128.38, −52.86]; p<0.00001, mean difference = −91.43, and 95% CI [−122.38, −60.49]; p=0.02, mean difference = −40.30, and 95% CI [−74.24, −6.36], resp.).
Compared with anti-inflammation medications and/or urate-lowering therapies, MSD monotherapy significantly decreased ESR (p<0.00001; mean difference = −8.11; 95% CI [−12.53, −3.69]) and CRP (p=0.03; mean difference = −3.21; 95% CI [−6.07, −0.36]).
Additionally, the adverse effects (AEs) of MSD were fewer (p<0.00001; OR = 0.08; 95% CI [0.05, 0.16]).
MSD are effective in the treatment of gouty arthritis through anti-inflammation and lowering urate.
However, the efficacy of MSD should be estimated with more RCTs.
American Psychological Association (APA)
Liu, Yafei& Huang, Ying& Wen, Cai-Yu-Zhu& Zhang, Jun-Jun& Xing, Guo-Lan& Tu, Shenghao…[et al.]. 2017. The Effects of Modified Simiao Decoction in the Treatment of Gouty Arthritis: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1154178
Modern Language Association (MLA)
Liu, Yafei…[et al.]. The Effects of Modified Simiao Decoction in the Treatment of Gouty Arthritis: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-12.
https://search.emarefa.net/detail/BIM-1154178
American Medical Association (AMA)
Liu, Yafei& Huang, Ying& Wen, Cai-Yu-Zhu& Zhang, Jun-Jun& Xing, Guo-Lan& Tu, Shenghao…[et al.]. The Effects of Modified Simiao Decoction in the Treatment of Gouty Arthritis: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1154178
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154178