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A New Strategy for Quality Evaluation and Identification of Representative Chemical Components in Polygonum multiflorum Thunb.
Joint Authors
Wang, Yi-Tao
Li, Yunxia
Peng, Cheng
Gong, Xiao-hong
Liu, Mei-chen
Li, Peng
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-24
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Polygonum multiflorum Thunb.
(HSW) is widely used as herb medicine and health food additive.
Recently, a series of HSW-induced hepatotoxicities have been reported and many studies have been carried out to investigate it.
But contradictory conclusions were drawn that might be caused by the inconsistent quality of market decoction pieces.
Therefore, the HSW decoction pieces quality was evaluated with a developed novel method in the paper.
25 batches of raw HSW (RHSW) and 21 batches of processed HSW (PHSW) samples were purchased from different provinces of China.
HPLC determination was performed to identify and detect the contents of 16 chemical compounds in herbal material.
Fingerprint similarity was analyzed using chromatography information and the results showed that most herbs were in good similarity.
Then, a comprehensive evaluation strategy based on principal component analysis with representative quality control indicators was developed to evaluate the quality of HSW samples.
And the rationality of the developed method was verified by HCA analysis.
The results showed that the herb from Dabashan, Sichuan Province, no matter RHSW or PHSW had the best quality.
Different representative components were selected for RHSW or PHSW decoction pieces which might be caused by the chemical reaction during processing.
And most PHSW were unqualified according to the requirement of Chinese Pharmacopeia which might take the responsibility for the toxicity of HSW.
American Psychological Association (APA)
Li, Yunxia& Gong, Xiao-hong& Liu, Mei-chen& Peng, Cheng& Li, Peng& Wang, Yi-Tao. 2017. A New Strategy for Quality Evaluation and Identification of Representative Chemical Components in Polygonum multiflorum Thunb.. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1154237
Modern Language Association (MLA)
Li, Yunxia…[et al.]. A New Strategy for Quality Evaluation and Identification of Representative Chemical Components in Polygonum multiflorum Thunb.. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1154237
American Medical Association (AMA)
Li, Yunxia& Gong, Xiao-hong& Liu, Mei-chen& Peng, Cheng& Li, Peng& Wang, Yi-Tao. A New Strategy for Quality Evaluation and Identification of Representative Chemical Components in Polygonum multiflorum Thunb.. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1154237
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154237