The use of vitamin D supplement in prevention of preterm labor
Author
Source
Journal of Babylon University : Journal of Applied and Pure Sciences
Issue
Vol. 25, Issue 2 (30 Jun. 2017), pp.651-661, 11 p.
Publisher
Publication Date
2017-06-30
Country of Publication
Iraq
No. of Pages
11
Main Subjects
Abstract EN
In modern obstetrics, preterm labor remain a major problem .
Infection during pregnancy is the commonest cause.
Since that vitamin D has been shown to act as an anti-inflammatory& immune modulator in the placenta so it could be used for preterm labor prevention.
In pregnant ladies ,higher levels of vitamin D were considerably associated with a lower risk of infection, preterm labor & preterm birth.
Vitamin D supplementation during pregnancy has long been a matter of concern, but updated researches showed that even a high dose supplementation in healthy pregnant ladies was safe & effective.
The aim of the study 1.
Determine the relationship between maternal 25-hydroxyvitamin D & the risk of spontaneous preterm birth before 37 completed weeks.
2.
Determine whether 4000 IU/day of vitamin D supplement prevent preterm birth in those with threatened preterm labor (premature uterine contraction)& those with early preterm labor(in the latent phase) .
the study was carried : 1.
at Babylon Teaching hospital for Maternity& pediatric in the obstetrical word.
2.out patient clinic.
A randomized clinical trial was done on (109) patients from 1 st of June 2014 to 1st of Jan 2015.
Their gestational age was of (24-<37completed weeks), Blood samples were taken from all of them for measurement of vitamin D level.
Those patients then divided into 2 groups: 1.
study group consist of 69 pregnant women who were presented with either threatened preterm labor or early preterm labor ( at the latent phase) were given a supplement of vitamin D (4000IU) daily till term & follow them for their progress of labor& 2.
Control group of 40 pregnant women at the same gestational age of the study group but without preterm labor.(just assess vitamin D level).
There was a significant association between low vitamin D level & preterm labor as preterm labor was inversely associated with pre delivery level.
The study found that (61.1%) of patients with threatened preterm labor & (75.8%) of patients with early preterm labor are presented with low vitamin D level , while (62.5%) of control group presented with sufficient vitamin D level.
There was (36.4%) reduction in proportion of early preterm labor as well as (83.3%) reduction in proportion of threatened preterm labor(premature uterine contraction) after vitamin D supplementation.
Conclusion: vitamin D supplement has a role in prevention of preterm labor especially in those with low pre delivery serum level & those with threatened preterm labor.-
American Psychological Association (APA)
Witwit, Suha J.. 2017. The use of vitamin D supplement in prevention of preterm labor. Journal of Babylon University : Journal of Applied and Pure Sciences،Vol. 25, no. 2, pp.651-661.
https://search.emarefa.net/detail/BIM-1154240
Modern Language Association (MLA)
Witwit, Suha J.. The use of vitamin D supplement in prevention of preterm labor. Journal of Babylon University : Journal of Applied and Pure Sciences Vol. 25, no. 2 (2017), pp.651-661.
https://search.emarefa.net/detail/BIM-1154240
American Medical Association (AMA)
Witwit, Suha J.. The use of vitamin D supplement in prevention of preterm labor. Journal of Babylon University : Journal of Applied and Pure Sciences. 2017. Vol. 25, no. 2, pp.651-661.
https://search.emarefa.net/detail/BIM-1154240
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 660-661
Record ID
BIM-1154240