Predictive Value of Positive Margins in Diagnostic Biopsies of Dysplastic Nevi
Joint Authors
Dickman, Jeffrey S.
Racette, Andrew J.
Haddad, Reem M.
Source
Dermatology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-29
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Dysplastic nevi (DN) are common and controversial and the best choice for management of DN after diagnosis is not always clear.
The presence of positive margins found on diagnostic biopsy is used by many dermatologists when deciding whether to re-excise these lesions.
In order to quantify the predictive value of positive margins in diagnostic biopsies of DN, we performed a review and analysis of the concordance between the histological findings of biopsies and their subsequent excisions.
A total of 122 pathology reports from diagnostic biopsies of DN with nevus cells present at the tissue margin were reviewed.
Within this sample, 68 total postbiopsy excisions had been performed.
The excisional pathology reports were reviewed for the presence of residual or recurrent nevus cells.
Residual nevus cells were reported in 29 of 63 available excisional pathology reports illustrating a positive predictive value (PPV) of positive margins in diagnostic biopsies of DN of 46.0%.
We present this value along with PPVs from the very few existing similar studies.
The quantified predictive value of positive margins in diagnostic biopsies is useful information for providers who must make decisions regarding the best treatment options for patients with DN.
The low PPV of positive margins lends further evidence that DN of moderate severity or less may simply be monitored.
American Psychological Association (APA)
Dickman, Jeffrey S.& Haddad, Reem M.& Racette, Andrew J.. 2020. Predictive Value of Positive Margins in Diagnostic Biopsies of Dysplastic Nevi. Dermatology Research and Practice،Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1154298
Modern Language Association (MLA)
Dickman, Jeffrey S.…[et al.]. Predictive Value of Positive Margins in Diagnostic Biopsies of Dysplastic Nevi. Dermatology Research and Practice No. 2020 (2020), pp.1-4.
https://search.emarefa.net/detail/BIM-1154298
American Medical Association (AMA)
Dickman, Jeffrey S.& Haddad, Reem M.& Racette, Andrew J.. Predictive Value of Positive Margins in Diagnostic Biopsies of Dysplastic Nevi. Dermatology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-4.
https://search.emarefa.net/detail/BIM-1154298
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154298