Toxic Epidermal Necrolysis (TEN)Stevens-Johnson Syndrome (SJS) Epidemiology and Mortality Rate at King Fahad Specialist Hospital (KFSH) in Qassim Region of Saudi Arabia: A Retrospective Study
Joint Authors
Alajaji, Abdullah
Chandra Shekaran, Jagannath
Mohammed Aldhabbah, Omar
Alhindi, Hajar Abdullah
Almazyad, Nouf Salem
Aljutayli, Ziyad Abdulrahman
Abaalkhail, Saleh
Alfouzan, Saleh
Source
Dermatology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-3, 3 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-09
Country of Publication
Egypt
No. of Pages
3
Main Subjects
Abstract EN
Background.
Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are life-threatening conditions caused by drug reactions.
There are multiple causative drugs and different risk factors associated with SJS/TEN.
Objectives.
To study the epidemiology of SJS/TEN and associated mortality rate in Qassim region, Saudi Arabia.
Methodology.
A retrospective chart review of all patients with the diagnosis of SJS/TEN who were admitted to King Fahad Specialist Hospital (KFSH) in Qassim region, Saudi Arabia, for the period between Jan 2014 to Jan 2019.
The Careware information health system is used at KFSH, and patients were identified searching the diagnosis SJS/TEN.
Results.
Total of 10 patients with diagnosis of SJS/TEN were admitted to KFSH for the period from Jan 2014 to Jan 2019.
Antibiotics were the culprit in 5 out of 10 patients.
9 out of 10 patients survived with good outcome.
One patient with the diagnosis of TEN died, given extensive skin involvement complicated by sepsis.
Conclusion.
Despite the limitation of this study given small sample size, this is the first study of its kind that discusses the epidemiology of SJS/TEN in Saudi Arabia.
We found the estimated incidence rate of SJS/TEN in Qassim region to be 7.6 cases per million person-years.
Antibiotics and antiepileptics were the culprits in 8 out of 10 patients.
American Psychological Association (APA)
Alajaji, Abdullah& Chandra Shekaran, Jagannath& Mohammed Aldhabbah, Omar& Alhindi, Hajar Abdullah& Almazyad, Nouf Salem& Aljutayli, Ziyad Abdulrahman…[et al.]. 2020. Toxic Epidermal Necrolysis (TEN)Stevens-Johnson Syndrome (SJS) Epidemiology and Mortality Rate at King Fahad Specialist Hospital (KFSH) in Qassim Region of Saudi Arabia: A Retrospective Study. Dermatology Research and Practice،Vol. 2020, no. 2020, pp.1-3.
https://search.emarefa.net/detail/BIM-1154310
Modern Language Association (MLA)
Alajaji, Abdullah…[et al.]. Toxic Epidermal Necrolysis (TEN)Stevens-Johnson Syndrome (SJS) Epidemiology and Mortality Rate at King Fahad Specialist Hospital (KFSH) in Qassim Region of Saudi Arabia: A Retrospective Study. Dermatology Research and Practice No. 2020 (2020), pp.1-3.
https://search.emarefa.net/detail/BIM-1154310
American Medical Association (AMA)
Alajaji, Abdullah& Chandra Shekaran, Jagannath& Mohammed Aldhabbah, Omar& Alhindi, Hajar Abdullah& Almazyad, Nouf Salem& Aljutayli, Ziyad Abdulrahman…[et al.]. Toxic Epidermal Necrolysis (TEN)Stevens-Johnson Syndrome (SJS) Epidemiology and Mortality Rate at King Fahad Specialist Hospital (KFSH) in Qassim Region of Saudi Arabia: A Retrospective Study. Dermatology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-3.
https://search.emarefa.net/detail/BIM-1154310
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154310