Pemphigus Vulgaris: A Clinical Study of 31 Cases (2004–2014) in Morocco
Joint Authors
Hjira, Naoufal
Hicham, Titou
Chahnoun, Fatima Zahra
Hanafi, Tarik
Mohammed, Boui
Source
Dermatology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-09-08
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Pemphigus vulgaris is a rare bullous autoimmune dermatosis whose evolution and prognosis are unpredictable.
Aim.
The objective was to analyze long-term outcomes in patients with pemphigus vulgaris by identifying the factors that are able to influence prognosis, in particular the phenotype of pemphigus vulgaris, age at onset, multiplicity of mucosal involvement, relapse and remission rates, and survival functions.
Methods.
A retrospective analysis of a cohort of 31 patients followed for pemphigus vulgaris during the period from January 2004 to January 2014.
Inclusion criteria were a diagnosis of pemphigus vulgaris confirmed by histopathology and direct immunofluorescence (DIF) and a period of follow-up of at least five years from the diagnosis.
The following information was collected by a single investigator.
Results.
In total, 67.7% of patients presented a mucocutaneous pemphigus vulgaris.
Male-female sex ratio was 2.4.
The median duration of patient’s follow-up was estimated at 7 (6–9) years.
Multiple mucosal involvement in the oral cavity and at other mucosal sites was significantly associated with severe mucocutaneous pemphigus vulgaris (p=0.01).
Multiple relapses were significantly associated with the disease severity (p=0.04).
Conclusion.
Poor prognosis factors were severe mucocutaneous type of pemphigus vulgaris and multiple mucosal involvement in the oral cavity and at other mucosal sites.
American Psychological Association (APA)
Hicham, Titou& Chahnoun, Fatima Zahra& Hanafi, Tarik& Hjira, Naoufal& Mohammed, Boui. 2020. Pemphigus Vulgaris: A Clinical Study of 31 Cases (2004–2014) in Morocco. Dermatology Research and Practice،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1154324
Modern Language Association (MLA)
Hicham, Titou…[et al.]. Pemphigus Vulgaris: A Clinical Study of 31 Cases (2004–2014) in Morocco. Dermatology Research and Practice No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1154324
American Medical Association (AMA)
Hicham, Titou& Chahnoun, Fatima Zahra& Hanafi, Tarik& Hjira, Naoufal& Mohammed, Boui. Pemphigus Vulgaris: A Clinical Study of 31 Cases (2004–2014) in Morocco. Dermatology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1154324
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154324