Effects of Acupuncture on Alzheimer’s Disease in Animal-Based Research
Joint Authors
Lee, Jun-Hwan
Park, Sunjung
Yang, Eun Jin
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-27
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Alzheimer’s disease (AD) is a chronic neurodegenerative disease characterized by the accumulation of amyloid beta (Aβ) plaques, neurofibrillary tangles, and severe functional deficits in the brain.
The pathogenesis and treatment of AD remain topics of investigation and significant global socioeconomic issues.
The effect of complementary medicine has been investigated in managing AD.
Acupuncture, a form of therapy practiced for more than 3000 years, has shown positive effects on several neurological disorders including AD.
Animal studies have evaluated the specific utility and neuropathological mechanisms addressed by acupoint manipulation; however, no study has summarized the relationships among different acupoints and their therapeutic effects in the context of AD.
Therefore, we reviewed the effects of acupuncture at different acupoints in animal models of AD.
In general, acupuncture produced therapeutic benefits in rodent models of AD.
Studies demonstrate the utility of GV20 as a valuable acupoint for electroacupuncture and manual acupuncture.
GV20 stimulation suppresses Aβ generation, improves glucose metabolism, and attenuates neuropathological features in various disease models.
However, a lack of sufficient evidence in preclinical and clinical studies makes these results controversial.
Additional studies are required to confirm the exact utility of specific acupoints in clinically managing AD.
American Psychological Association (APA)
Park, Sunjung& Lee, Jun-Hwan& Yang, Eun Jin. 2017. Effects of Acupuncture on Alzheimer’s Disease in Animal-Based Research. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1154348
Modern Language Association (MLA)
Park, Sunjung…[et al.]. Effects of Acupuncture on Alzheimer’s Disease in Animal-Based Research. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1154348
American Medical Association (AMA)
Park, Sunjung& Lee, Jun-Hwan& Yang, Eun Jin. Effects of Acupuncture on Alzheimer’s Disease in Animal-Based Research. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1154348
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154348