Effects of Acupuncture on Alzheimer’s Disease in Animal-Based Research

Joint Authors

Lee, Jun-Hwan
Park, Sunjung
Yang, Eun Jin

Source

Evidence-Based Complementary and Alternative Medicine

Issue

Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-5, 5 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2017-09-27

Country of Publication

Egypt

No. of Pages

5

Main Subjects

Medicine

Abstract EN

Alzheimer’s disease (AD) is a chronic neurodegenerative disease characterized by the accumulation of amyloid beta (Aβ) plaques, neurofibrillary tangles, and severe functional deficits in the brain.

The pathogenesis and treatment of AD remain topics of investigation and significant global socioeconomic issues.

The effect of complementary medicine has been investigated in managing AD.

Acupuncture, a form of therapy practiced for more than 3000 years, has shown positive effects on several neurological disorders including AD.

Animal studies have evaluated the specific utility and neuropathological mechanisms addressed by acupoint manipulation; however, no study has summarized the relationships among different acupoints and their therapeutic effects in the context of AD.

Therefore, we reviewed the effects of acupuncture at different acupoints in animal models of AD.

In general, acupuncture produced therapeutic benefits in rodent models of AD.

Studies demonstrate the utility of GV20 as a valuable acupoint for electroacupuncture and manual acupuncture.

GV20 stimulation suppresses Aβ generation, improves glucose metabolism, and attenuates neuropathological features in various disease models.

However, a lack of sufficient evidence in preclinical and clinical studies makes these results controversial.

Additional studies are required to confirm the exact utility of specific acupoints in clinically managing AD.

American Psychological Association (APA)

Park, Sunjung& Lee, Jun-Hwan& Yang, Eun Jin. 2017. Effects of Acupuncture on Alzheimer’s Disease in Animal-Based Research. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1154348

Modern Language Association (MLA)

Park, Sunjung…[et al.]. Effects of Acupuncture on Alzheimer’s Disease in Animal-Based Research. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1154348

American Medical Association (AMA)

Park, Sunjung& Lee, Jun-Hwan& Yang, Eun Jin. Effects of Acupuncture on Alzheimer’s Disease in Animal-Based Research. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1154348

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1154348