Efficacy and Safety of the TCM Qi-Supplementing Therapy in Patients with Myasthenia Gravis: A Systematic Review and Meta-Analysis
Joint Authors
Yang, Xi-qian
Liu, Ling
Yang, Wen-yu
Dong, Huan-huan
Yang, Yi-ran
Li, Yun
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-03
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Background.
The Traditional Chinese Medicine (TCM) Qi-supplementing therapy has been used widely for treating myasthenia gravis (MG) in China.
The purpose of this meta-analysis was to evaluate the efficacy and safety of Qi-supplementing therapy as an adjunctive therapy in MG patients.
Methods.
Seven electronic databases were searched through June 2016.
Randomized controlled trials (RCTs) evaluating the add-on effect of Qi-supplementing therapy in MG patients were included.
The outcome measures were the total effective rate, relapse rate, and adverse events.
Results.
Twenty-three RCTs involving 1,691 MG patients were included.
The included studies were of low-to-moderate quality.
Meta-analysis showed that Qi-supplementing therapy combined with Western medicine (WM) significantly improved the total response rate and reduced the relapse risk during 6–24 months of follow-up.
Subgroup analysis showed that Qi-supplementing therapy only affected the total response rate within the first 6 months of treatment.
Moreover, the rate of adverse events was lower with the addition of Qi-supplementing therapy to WM than with WM only.
Conclusions.
Short-term Qi-supplementing therapy combined with WM appears to be superior to WM for improving the total response rate and reducing the relapse rate.
However, more high-quality RCTs are warranted owing to methodological flaws of previous trials.
American Psychological Association (APA)
Yang, Xi-qian& Liu, Ling& Yang, Wen-yu& Dong, Huan-huan& Yang, Yi-ran& Li, Yun. 2017. Efficacy and Safety of the TCM Qi-Supplementing Therapy in Patients with Myasthenia Gravis: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1154350
Modern Language Association (MLA)
Yang, Xi-qian…[et al.]. Efficacy and Safety of the TCM Qi-Supplementing Therapy in Patients with Myasthenia Gravis: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1154350
American Medical Association (AMA)
Yang, Xi-qian& Liu, Ling& Yang, Wen-yu& Dong, Huan-huan& Yang, Yi-ran& Li, Yun. Efficacy and Safety of the TCM Qi-Supplementing Therapy in Patients with Myasthenia Gravis: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1154350
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154350