Mechanical Stimulation of the HT7 Acupuncture Point to Reduce Ethanol Self-Administration in Rats
Joint Authors
Ryu, Yeon Hee
Choi, Kwang-Ho
Kang, Suk-Yun
Ahn, Seong Hun
Moon, Ji-Young
Kim, Junbeom
Kwon, O. Sang
Cho, Seong-Jin
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-30
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Alcoholism, which is a disabling addiction disorder, is a major public health problem worldwide.
The present study was designed to determine whether the application of acupuncture at the Shenmen (HT7) point suppresses voluntary alcohol consumption in addicted rats and whether this suppressive effect is potentiated by the administration of naltrexone.
Methods.
Rats were initially trained to self-administer a sucrose solution by operating a lever.
A mechanical acupuncture instrument (MAI) for objective mechanical stimulation was used on rats whose baseline response had been determined.
In addition, the effect of HT7 acupuncture on beta-endorphin concentration and ethanol intake via naltrexone were investigated in different groups.
Results.
We found that ethanol intake and beta-endorphin level in rats being treated with the MAI at the HT7 point reduced significantly.
The treatment of naltrexone at high doses reduced the ethanol intake and low-dose injection of naltrexone in conjunction with the MAI also suppressed ethanol intake.
Conclusions.
The results of the current study indicate that using the MAI at the HT7 point effectively reduces ethanol consumption in rats.
Furthermore, the coadministration of the MAI and a low dose of naltrexone can produce some more potent reducing effect of ethanol intake than can acupuncture alone.
American Psychological Association (APA)
Kang, Suk-Yun& Kwon, O. Sang& Moon, Ji-Young& Cho, Seong-Jin& Choi, Kwang-Ho& Kim, Junbeom…[et al.]. 2017. Mechanical Stimulation of the HT7 Acupuncture Point to Reduce Ethanol Self-Administration in Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1154362
Modern Language Association (MLA)
Kang, Suk-Yun…[et al.]. Mechanical Stimulation of the HT7 Acupuncture Point to Reduce Ethanol Self-Administration in Rats. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1154362
American Medical Association (AMA)
Kang, Suk-Yun& Kwon, O. Sang& Moon, Ji-Young& Cho, Seong-Jin& Choi, Kwang-Ho& Kim, Junbeom…[et al.]. Mechanical Stimulation of the HT7 Acupuncture Point to Reduce Ethanol Self-Administration in Rats. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1154362
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154362