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Preparation of a Nanoemulsion with Carapa guianensis Aublet (Meliaceae) Oil by a Low-EnergySolvent-Free Method and Evaluation of Its Preliminary Residual Larvicidal Activity
Joint Authors
de Almeida, Fernanda B.
Lira-Guedes, Ana Cláudia
Guedes, Marcelino Carneiro
Jesus, Flávia L. M.
Duarte, Jonatas L.
Oliveira, Anna E. M. F. M.
Cruz, Rodrigo A. S.
Souto, Raimundo N. P.
Ferreira, Ricardo M. A.
Kelmann, Regina Gendzelevski
Solans, Conxita
Carvalho, José Carlos Tavares
Fernandes, Caio Pinho
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-17
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Andiroba (Carapa guianensis) seeds are the source of an oil with a wide range of biological activities and ethnopharmacological uses.
However, few studies have devoted attention to innovative formulations, including nanoemulsions.
The present study aimed to obtain a colloidal system with the andiroba oil using a low-energy and organic-solvent-free method.
Moreover, the preliminary residual larvicidal activity of the nanoemulsion against Aedes aegypti was evaluated.
Oleic and palmitic acids were the major fatty acids, in addition to the phytosterol β-sitosterol and limonoids (tetranortriterpenoids).
The required hydrophile-lipophile was around 11.0 and the optimal nanoemulsion was obtained using polysorbate 85.
The particle size distribution suggested the presence of small droplets (mean diameter around 150 nm) and low polydispersity index (around 0.150).
The effect of temperature on particle size distribution revealed that no major droplet size increase occurred.
The preliminary residual larvicidal assay suggested that the mortality increased as a function of time.
The present study allowed achievement of a potential bioactive oil in water nanoemulsion that may be a promising controlled release system.
Moreover, the ecofriendly approach involved in the preparation associated with the great bioactive potential of C.
guianensis makes this nanoemulsion very promising for valorization of this Amazon raw material.
American Psychological Association (APA)
Jesus, Flávia L. M.& de Almeida, Fernanda B.& Duarte, Jonatas L.& Oliveira, Anna E. M. F. M.& Cruz, Rodrigo A. S.& Souto, Raimundo N. P.…[et al.]. 2017. Preparation of a Nanoemulsion with Carapa guianensis Aublet (Meliaceae) Oil by a Low-EnergySolvent-Free Method and Evaluation of Its Preliminary Residual Larvicidal Activity. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1154389
Modern Language Association (MLA)
Jesus, Flávia L. M.…[et al.]. Preparation of a Nanoemulsion with Carapa guianensis Aublet (Meliaceae) Oil by a Low-EnergySolvent-Free Method and Evaluation of Its Preliminary Residual Larvicidal Activity. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1154389
American Medical Association (AMA)
Jesus, Flávia L. M.& de Almeida, Fernanda B.& Duarte, Jonatas L.& Oliveira, Anna E. M. F. M.& Cruz, Rodrigo A. S.& Souto, Raimundo N. P.…[et al.]. Preparation of a Nanoemulsion with Carapa guianensis Aublet (Meliaceae) Oil by a Low-EnergySolvent-Free Method and Evaluation of Its Preliminary Residual Larvicidal Activity. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1154389
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154389