The Antibacterial Activity of Mass Galla Chinesis et Camelliae Fermentata on Helicobacter pylori Infection
Joint Authors
Ye, Hui
Yu, Jing
Zhang, Xuezhi
Li, Jiang
Li, Ning
Shi, Zong-ming
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-12
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Mass Galla chinesis et camelliae Fermentata (Chinese gall leaven, CGL) was investigated for activities against Helicobacter pylori (H.
pylori) both in vitro and in vivo.
The agar dilution method and time-kill curves, as in vitro assays and an in vivo study using a Kunming mice model, were performed.
CGL demonstrated a strong anti-Helicobacter pylori activity in vitro with the minimal inhibitory concentrations (MICs) against multiple H.
pylori strains of 0.5~8 mg/ml and the decreasing trend time-kill curves when increasing CGL concentrations.
H.
pylori eradication rates in vivo were evaluated based on rapid urease test (RUT) and histopathologic criteria.
Results revealed that the eradication rates in the CGL groups were 40% (4/10) in the high dosage group, 33% (4/11) in the medium dosage group, and 18% (2/11) in the low dosage group, with the difference between the high dosage and H.
pylori control groups being significant (P=0.035).
The H.
pylori colonization scores could be reduced partly by CGL.
These in vivo results demonstrated that CGL in a rationally high dosage might be the most effective.
American Psychological Association (APA)
Yu, Jing& Ye, Hui& Li, Jiang& Li, Ning& Shi, Zong-ming& Zhang, Xuezhi. 2018. The Antibacterial Activity of Mass Galla Chinesis et Camelliae Fermentata on Helicobacter pylori Infection. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1154400
Modern Language Association (MLA)
Yu, Jing…[et al.]. The Antibacterial Activity of Mass Galla Chinesis et Camelliae Fermentata on Helicobacter pylori Infection. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1154400
American Medical Association (AMA)
Yu, Jing& Ye, Hui& Li, Jiang& Li, Ning& Shi, Zong-ming& Zhang, Xuezhi. The Antibacterial Activity of Mass Galla Chinesis et Camelliae Fermentata on Helicobacter pylori Infection. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1154400
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154400