Flavonoid Composition and Biological Activities of Ethanol Extracts of Caryocar coriaceum Wittm., a Native Plant from Caatinga Biome
Joint Authors
Vasconcelos, Fábio Roger
Tomiotto-Pellissier, Fernanda
Maia Morais, Selene
Alves, Daniela Ribeiro
Silva, Isaac Neto Goes da
Araujo de Sousa, Halisson
Assolini, João Paulo
Freire, Francisco das Chagas Oliveira
Miranda, Milena Menegazzo
Conchon-Costa, Ivete
Pavanelli, Wander Rogério
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-07
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Caryocar coriaceum fruits, found in Brazilian Cerrado and Caatinga, are commonly used as food and in folk medicine, as anti-inflammatory, bactericide, fungicide, leishmanicide, and nematicide.
Due to the biological potential of this plant, this study focuses on the evaluation of antifungal and antileishmanial activities, including anticholinesterase and antioxidant tests, correlating with total phenols and flavonoids content.
Peel extracts contain higher yield of phenols and flavonoids as analyzed by spectrophotometric methods.
HPLC analysis of flavonoids revealed that isoquercitrin is the main flavonoid in both parts of the fruit, and peel extract showed the best antioxidant activity.
In the inhibition of the acetylcholinesterase assay, both extracts demonstrate action comparable to physostigmine.
The antimicrobial activity of extracts was evaluated against strains of Malassezia sp.
and Microsporum canis, using the broth microdilution technique, in which the extracts showed similar MIC and MFC.
The extracts present antileishmanial activity and low toxicity on murine macrophages and erythrocytes.
Therefore, these results suggest a potential for the application of C.
coriaceum fruit’s ethanol extracts in the treatment against dermatophyte fungi and leishmaniasis, probably due to the presence of active flavonoids.
Further in vivo studies are recommended aiming at the development of possible new pharmaceutical compounds.
American Psychological Association (APA)
Alves, Daniela Ribeiro& Maia Morais, Selene& Tomiotto-Pellissier, Fernanda& Miranda, Milena Menegazzo& Vasconcelos, Fábio Roger& Silva, Isaac Neto Goes da…[et al.]. 2017. Flavonoid Composition and Biological Activities of Ethanol Extracts of Caryocar coriaceum Wittm., a Native Plant from Caatinga Biome. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1154405
Modern Language Association (MLA)
Alves, Daniela Ribeiro…[et al.]. Flavonoid Composition and Biological Activities of Ethanol Extracts of Caryocar coriaceum Wittm., a Native Plant from Caatinga Biome. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1154405
American Medical Association (AMA)
Alves, Daniela Ribeiro& Maia Morais, Selene& Tomiotto-Pellissier, Fernanda& Miranda, Milena Menegazzo& Vasconcelos, Fábio Roger& Silva, Isaac Neto Goes da…[et al.]. Flavonoid Composition and Biological Activities of Ethanol Extracts of Caryocar coriaceum Wittm., a Native Plant from Caatinga Biome. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1154405
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154405