A Systematic Review about the Efficacy and Safety of Tripterygium wilfordii Hook.f. Preparations Used for the Management of Rheumatoid Arthritis
Joint Authors
Zhang, Xu
Li, Guo-chun
Zhou, Xueping
Wang, Jing
Chen, Na
Fang, Liang
Feng, Zhe
Mucelli, Attilio
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-08
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Tripterygium wilfordii Hook.f.
(TWHF) is a traditional Chinese herb long used for rheumatoid arthritis (RA) treatment, in modern times, often in the form of various Tripterygium wilfordii Hook.f.
preparations (TWPs).
This systematic review and meta-analysis focuses on analyzing the clinical efficacy and safety of TWPs in the treatment of RA.
Databases were searched to collect the randomized controlled trials (RCTs) on TWPs treating RA published on or before April 10, 2017.
Data from 11 studies were included in this meta-analysis.
Compared with the control group, TWPs can increase effectiveness, while decreasing erythrocyte sedimentation rate (ESR), rheumatoid factor (RF), C-reactive protein (CRP), and risk of adverse events.
TWPs treatment was also more effective than treatment by conventional western medicine (CWM) and Chinese patent medicine or placebo (COP).
TWPs significantly decreased the risk of adverse events compared with the CWM group, but not compared with the COP group.
Current evidence shows that TWPs are more effective than other western or Chinese medicines we included in this meta-analysis for RA treatment with relatively lower toxicity.
American Psychological Association (APA)
Wang, Jing& Chen, Na& Fang, Liang& Feng, Zhe& Li, Guo-chun& Mucelli, Attilio…[et al.]. 2018. A Systematic Review about the Efficacy and Safety of Tripterygium wilfordii Hook.f. Preparations Used for the Management of Rheumatoid Arthritis. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1154423
Modern Language Association (MLA)
Wang, Jing…[et al.]. A Systematic Review about the Efficacy and Safety of Tripterygium wilfordii Hook.f. Preparations Used for the Management of Rheumatoid Arthritis. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1154423
American Medical Association (AMA)
Wang, Jing& Chen, Na& Fang, Liang& Feng, Zhe& Li, Guo-chun& Mucelli, Attilio…[et al.]. A Systematic Review about the Efficacy and Safety of Tripterygium wilfordii Hook.f. Preparations Used for the Management of Rheumatoid Arthritis. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1154423
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154423