Efficacy and Safety of Compound Kushen Injection on Patients with Advanced Colon Cancer: A Meta-Analysis of Randomized Controlled Trials
Joint Authors
Yu, Lixiu
Zhou, Ying
Yang, Yu
Lu, Furong
Fan, Yeqin
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-12
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objective.
The efficacy and safety of Compound Kushen Injection (CKI) on advanced colon cancer remain controversial.
We undertook a systematic meta-analysis of randomized controlled clinical studies on this issue.
Methods.
A comprehensive literature search was conducted by searching the following electronic databases: PubMed, Cochrane, Chinese Biological Medical disc, Chinese National Knowledge Infrastructure, and Wan-Fang Database in China by the end of January 31, 2017, without language restriction.
Meta-analysis was performed by using the random effects model to estimate the summary odd ratio (OR) with 95% confidence interval (CI) according to the study design.
Stata 12.0 software was used for data analysis.
The heterogeneity, sensitivity, and publication bias were assessed, respectively.
Results.
A total of 14 trials met the inclusion criteria in present meta-analysis.
The results suggested that CKI combined with chemotherapeutic drugs was favorable for the treatment of advanced colon cancer and could improve the patients’ life quality.
Funnel plot analysis and Egger’s test suggested that there was not significant publication bias, and the sensitivity analysis indicated stable results.
Conclusion.
The current evidence suggested that CKI is favorable to improve the efficacy of chemotherapeutic drugs in patients with advanced colon cancer.
American Psychological Association (APA)
Yu, Lixiu& Zhou, Ying& Yang, Yu& Lu, Furong& Fan, Yeqin. 2017. Efficacy and Safety of Compound Kushen Injection on Patients with Advanced Colon Cancer: A Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1154445
Modern Language Association (MLA)
Yu, Lixiu…[et al.]. Efficacy and Safety of Compound Kushen Injection on Patients with Advanced Colon Cancer: A Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1154445
American Medical Association (AMA)
Yu, Lixiu& Zhou, Ying& Yang, Yu& Lu, Furong& Fan, Yeqin. Efficacy and Safety of Compound Kushen Injection on Patients with Advanced Colon Cancer: A Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1154445
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154445