Cannabis Essential Oil: A Preliminary Study for the Evaluation of the Brain Effects
Joint Authors
Firenzuoli, Fabio
Gori, Luigi
Macchi, Claudio
Gulluni, Nadia
Re, Tania
Loiacono, Idalba
Lanzo, Giovanni
Epifani, Francesco
Bragazzi, Nicola Luigi
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-17
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
We examined the effects of essential oil from legal (THC <0.2% w/v) hemp variety on the nervous system in 5 healthy volunteers.
GC/EIMS and GC/FID analysis of the EO showed that the main components were myrcene and β-caryophyllene.
The experiment consisted of measuring autonomic nervous system (ANS) parameters; evaluations of the mood state; and electroencephalography (EEG) recording before treatment, during treatment, and after hemp inhalation periods as compared with control conditions.
The results revealed decreased diastolic blood pressure, increased heart rate, and significant increased skin temperature.
The subjects described themselves as more energetic, relaxed, and calm.
The analysis EEG showed a significant increase in the mean frequency of alpha (8–13 Hz) and significant decreased mean frequency and relative power of beta 2 (18,5–30 Hz) waves.
Moreover, an increased power, relative power, and amplitude of theta (4–8 Hz) and alpha brain waves activities and an increment in the delta wave (0,5–4 Hz) power and relative power was recorded in the posterior region of the brain.
These results suggest that the brain wave activity and ANS are affected by the inhalation of the EO of Cannabis sativa suggesting a neuromodular activity in cases of stress, depression, and anxiety.
American Psychological Association (APA)
Gulluni, Nadia& Re, Tania& Loiacono, Idalba& Lanzo, Giovanni& Gori, Luigi& Macchi, Claudio…[et al.]. 2018. Cannabis Essential Oil: A Preliminary Study for the Evaluation of the Brain Effects. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1154452
Modern Language Association (MLA)
Gulluni, Nadia…[et al.]. Cannabis Essential Oil: A Preliminary Study for the Evaluation of the Brain Effects. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1154452
American Medical Association (AMA)
Gulluni, Nadia& Re, Tania& Loiacono, Idalba& Lanzo, Giovanni& Gori, Luigi& Macchi, Claudio…[et al.]. Cannabis Essential Oil: A Preliminary Study for the Evaluation of the Brain Effects. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1154452
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154452