A Traditional Herbal Formula Xianlinggubao for Pain Control and Function Improvement in Patients with Knee and Hand Osteoarthritis: A Multicenter, Randomized, Open-Label, Controlled Trial
Joint Authors
Qin, Ling
Shi, Lei
Wang, Fei
Xue, Qing-Yun
Pei, Fuxing
Zhang, Yaonan
Zhu, Hanmin
Shi, Zhanjun
Tao, Tianzun
Li, Zhihua
Zeng, Ping
Wang, Xiaobing
Ji, Quan
Wang, Kunzheng
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-12
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Evidence of efficacy of a traditional herbal formula Xianlinggubao (XLGB) for treatment of osteoarthritis (OA) is limited.
The present study was designed to evaluate the efficacy of XLGB in the management of patients with knee and hand OA.
This was a multicenter, stratified, open-label, randomized controlled trial conducted at six centers in China.
People aged 40 or above, diagnosed with OA of the knee or hand, were randomly assigned to the XLGB treatment group or watchful waiting control group.
Main outcome measures were the changes in the numeric pain rating scales (NPRS) and the Western Ontario and McMaster Universities Arthritis Index (WOMAC) or the Australian/Canadian Osteoarthritis Hand Index (AUSCAN) scores, from baseline to 6 months.
In total 534 patients (272 to XLGB and 262 to control group) received interventions.
Participants in the XLGB group exhibited significant improvement in NPRS (P<0.001) and WOMAC score (P<0.001) or AUSCAN score (P<0.001) compared to control group.
Treatment with XLGB at current regime significantly reduced pain and improved function of the knee and hand in patients with OA over a 6-month period, implying that XLGB could be suggested as an alternative treatment for patients with knee or hand OA.
American Psychological Association (APA)
Wang, Fei& Shi, Lei& Zhang, Yaonan& Wang, Kunzheng& Pei, Fuxing& Zhu, Hanmin…[et al.]. 2018. A Traditional Herbal Formula Xianlinggubao for Pain Control and Function Improvement in Patients with Knee and Hand Osteoarthritis: A Multicenter, Randomized, Open-Label, Controlled Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1154481
Modern Language Association (MLA)
Wang, Fei…[et al.]. A Traditional Herbal Formula Xianlinggubao for Pain Control and Function Improvement in Patients with Knee and Hand Osteoarthritis: A Multicenter, Randomized, Open-Label, Controlled Trial. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1154481
American Medical Association (AMA)
Wang, Fei& Shi, Lei& Zhang, Yaonan& Wang, Kunzheng& Pei, Fuxing& Zhu, Hanmin…[et al.]. A Traditional Herbal Formula Xianlinggubao for Pain Control and Function Improvement in Patients with Knee and Hand Osteoarthritis: A Multicenter, Randomized, Open-Label, Controlled Trial. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1154481
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154481