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Systems Pharmacological Approach to the Effect of Bulsu-san Promoting Parturition
Joint Authors
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-29
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Bulsu-san (BSS) has been commonly used in oriental medicine for pregnant women in East Asia.
The purpose of this research was to elucidate the effect of BSS on ease of parturition using a systems-level in silico analytic approach.
Research results show that BSS is highly connected to the parturition related pathways, biological processes, and organs.
There were numerous interactions between most compounds of BSS and multiple target genes, and this was confirmed using herb-compound-target network, target-pathway network, and gene ontology analysis.
Furthermore, the mRNA expression of relevant target genes of BSS was elevated significantly in related organ tissues, such as those of the uterus, placenta, fetus, hypothalamus, and pituitary gland.
This study used a network analytical approach to demonstrate that Bulsu-san (BSS) is closely related to the parturition related pathways, biological processes, and organs.
It is meaningful that this systems-level network analysis result strengthens the basis of clinical applications of BSS on ease of parturition.
American Psychological Association (APA)
Suh, Su Yeon& An, Won G.. 2017. Systems Pharmacological Approach to the Effect of Bulsu-san Promoting Parturition. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-15.
https://search.emarefa.net/detail/BIM-1154485
Modern Language Association (MLA)
Suh, Su Yeon& An, Won G.. Systems Pharmacological Approach to the Effect of Bulsu-san Promoting Parturition. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-15.
https://search.emarefa.net/detail/BIM-1154485
American Medical Association (AMA)
Suh, Su Yeon& An, Won G.. Systems Pharmacological Approach to the Effect of Bulsu-san Promoting Parturition. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-15.
https://search.emarefa.net/detail/BIM-1154485
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154485