The Antioxidative, Antiaging, and Hepatoprotective Effects of Alkali-Extractable Polysaccharides by Agaricus bisporus
Joint Authors
Jing, Huijuan
Zhang, Jianjun
Li, Shangshang
Ren, Zhenzhen
Gao, Zheng
Jia, Le
Li, Juan
Wang, Wenshuai
Wang, Xiuxiu
Song, Xinling
Gong, Zhiyuan
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-22
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
The aim of this work was designed to investigate the antioxidant, antiaging, and hepatoprotective effects of alkali-extractable polysaccharides (AlAPS) and their three purified fractions (AlAPS-1, AlAPS-2, and AlAPS-3) from Agaricus bisporus in D-galactose induced aging mice.
For in vitro antioxidant analysis, both AlAPS and its fractions exhibited moderate reducing power, Fe2+-chelating activities, and potent scavenging activities on hydroxyl and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals.
The in vivo results demonstrated that the polysaccharides, especially AlAPS-2, showed potential antiaging and hepatoprotective effects by enhancing the antioxidant status, decreasing serum hepatic enzyme activities, and improving the lipid metabolism.
This study suggested that the polysaccharides extracted and purified from A.
bisporus could be exploited as a potent dietary supplement to attenuate aging and prevent age-related diseases.
American Psychological Association (APA)
Li, Shangshang& Li, Juan& Zhang, Jianjun& Wang, Wenshuai& Wang, Xiuxiu& Jing, Huijuan…[et al.]. 2017. The Antioxidative, Antiaging, and Hepatoprotective Effects of Alkali-Extractable Polysaccharides by Agaricus bisporus. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1154502
Modern Language Association (MLA)
Li, Shangshang…[et al.]. The Antioxidative, Antiaging, and Hepatoprotective Effects of Alkali-Extractable Polysaccharides by Agaricus bisporus. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-12.
https://search.emarefa.net/detail/BIM-1154502
American Medical Association (AMA)
Li, Shangshang& Li, Juan& Zhang, Jianjun& Wang, Wenshuai& Wang, Xiuxiu& Jing, Huijuan…[et al.]. The Antioxidative, Antiaging, and Hepatoprotective Effects of Alkali-Extractable Polysaccharides by Agaricus bisporus. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1154502
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154502