![](/images/graphics-bg.png)
The Anti-Inflammatory Effects of a Yin Zhi Huang Soup in an Experimental Autoimmune Prostatitis Rat Model
Joint Authors
Deng, Longsheng
Zhang, Xikui
Zhu, Weikun
Lu, Taikun
Chen, Jinchun
Zou, Qiang
Zheng, Qizhong
Chen, Junying
Jiang, Changming
Jin, Guanyu
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-21
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
The present study aimed to investigate the therapeutic effects of the Chinese herbal medicine Yin Zhi Huang soup (YZS) in an experimental autoimmune prostatitis (EAP) rat model.
In total, 48 rats were randomly divided into the following four groups (n=12/group): saline group, pathological model group, Qianlietai group, and YZS group.
We determined the average wet weight of the prostate tissue, the ratio of the wet weight of the prostate tissue to body weight, tumor necrosis factor-alpha (TNF-α) levels in the blood serum, the expression of inducible nitric oxide synthase (iNOS) in the rats’ prostate tissues, and the pathological changes in the prostate tissue using light microscopy.
YZS reduced the rats’ prostate wet weight, the ratio of the prostate wet weight to body weight, and TNF-α levels in the blood serum and inhibited the expression of iNOS in the rats’ prostate tissues (P<0.05).
Following YZS treatment, the pathological changes in the rats’ prostates were improved compared with those in the model group (P<0.05).
Furthermore, YZS treatment reduced inflammatory changes in the prostate tissue.
It also significantly suppressed proinflammatory cytokines, such as TNF-α, and chemokines, such as iNOS, in the rat model of EAP.
American Psychological Association (APA)
Deng, Longsheng& Zhang, Xikui& Zhu, Weikun& Lu, Taikun& Chen, Jinchun& Zou, Qiang…[et al.]. 2017. The Anti-Inflammatory Effects of a Yin Zhi Huang Soup in an Experimental Autoimmune Prostatitis Rat Model. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1154506
Modern Language Association (MLA)
Deng, Longsheng…[et al.]. The Anti-Inflammatory Effects of a Yin Zhi Huang Soup in an Experimental Autoimmune Prostatitis Rat Model. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1154506
American Medical Association (AMA)
Deng, Longsheng& Zhang, Xikui& Zhu, Weikun& Lu, Taikun& Chen, Jinchun& Zou, Qiang…[et al.]. The Anti-Inflammatory Effects of a Yin Zhi Huang Soup in an Experimental Autoimmune Prostatitis Rat Model. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1154506
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154506