A New Chinese Medicine Intestine Formula Greatly Improves the Effect of Aminosalicylate on Ulcerative Colitis
Joint Authors
Liu, Baohai
Piao, Xuehua
Guo, Lianyi
Wang, Guijun
Sun, Weihua
Gao, Leming
Zheng, Xuefeng
Fang, Yanli
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-20
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Ulcerative colitis (UC) is a chronic lifelong inflammatory disorder of the colon.
Current medical treatment of UC relies predominantly on the use of traditional drugs, including aminosalicylates, corticosteroids, and immunosuppressants, which failed to effectively control this disease’s progression and produced various side effects.
Here, we report a new Chinese medicine intestine formula (CIF) which greatly improved the effect of mesalazine, an aminosalicylate, on UC.
In the present study, 60 patients with chronic UC were treated with oral mesalazine alone or in combination with CIF enema.
The combination of mesalazine and CIF greatly and significantly improved the clinical symptoms and colon mucosal condition and improved the Mayo Clinic Disease Activity Index and health-related quality of life, when compared to mesalazine alone.
In particular, the addition of CIF further decreased serum levels of tumor necrosis factor-alpha and hypersensitivity C-reactive protein but in contrast increased interleukin-4.
Thus, the results demonstrate the beneficial role of CIF in UC treatment, which may be mediated by the regulation of inflammation.
American Psychological Association (APA)
Liu, Baohai& Piao, Xuehua& Guo, Lianyi& Wang, Guijun& Sun, Weihua& Gao, Leming…[et al.]. 2017. A New Chinese Medicine Intestine Formula Greatly Improves the Effect of Aminosalicylate on Ulcerative Colitis. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1154508
Modern Language Association (MLA)
Liu, Baohai…[et al.]. A New Chinese Medicine Intestine Formula Greatly Improves the Effect of Aminosalicylate on Ulcerative Colitis. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1154508
American Medical Association (AMA)
Liu, Baohai& Piao, Xuehua& Guo, Lianyi& Wang, Guijun& Sun, Weihua& Gao, Leming…[et al.]. A New Chinese Medicine Intestine Formula Greatly Improves the Effect of Aminosalicylate on Ulcerative Colitis. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1154508
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154508