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Supercritical Fluid Extraction of Pyrrolidine Alkaloid from Leaves of Piper amalago L.
Joint Authors
Carrara, V. S.
Faiões, V. S.
Cunha-Júnior, E. F.
Torres-Santos, E. C.
Cortez, D. A. G.
Cardozo-Filho, Lucio
dos Santos Garcia, Vitor Augusto
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-02
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Supercritical fluid extraction was used to extract the alkaloid N-[7-(3′,4′-methylenedioxyphenyl)-2(Z),4(Z)-heptadienoyl]pyrrolidine from leaves of Piper amalago L.
A three-level orthogonal array design matrix, OAD OA9(34), was used for optimization of the parameters of supercritical extraction of the alkaloid, employing supercritical carbon dioxide: extraction time (20, 40, and 60 min), temperature (40, 50, and 60°C), pressure (150, 200, and 250 bar), and the use of cosolvents (ethanol, methanol, and propyleneglycol).
All parameters had significant effect on the alkaloid yield.
The alkaloid yield after 60 min of extraction without cosolvents at 9 different conditions (32) in terms of temperature (40, 50, and 60°C) and pressure (150, 200, and 250 bar) was also evaluated.
The optimal yield (≈3.8 mg g−1) was obtained with supercritical CO2 + methanol (5% v : v) at 40°C and 200 bar for 60 min of extraction.
American Psychological Association (APA)
Carrara, V. S.& Cardozo-Filho, Lucio& dos Santos Garcia, Vitor Augusto& Faiões, V. S.& Cunha-Júnior, E. F.& Torres-Santos, E. C.…[et al.]. 2017. Supercritical Fluid Extraction of Pyrrolidine Alkaloid from Leaves of Piper amalago L.. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1154540
Modern Language Association (MLA)
Carrara, V. S.…[et al.]. Supercritical Fluid Extraction of Pyrrolidine Alkaloid from Leaves of Piper amalago L.. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1154540
American Medical Association (AMA)
Carrara, V. S.& Cardozo-Filho, Lucio& dos Santos Garcia, Vitor Augusto& Faiões, V. S.& Cunha-Júnior, E. F.& Torres-Santos, E. C.…[et al.]. Supercritical Fluid Extraction of Pyrrolidine Alkaloid from Leaves of Piper amalago L.. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1154540
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154540