External Use of Propolis for Oral, Skin, and Genital Diseases: A Systematic Review and Meta-Analysis
Joint Authors
Shin, Byung-Cheul
Sung, Soo-Hyun
Choi, Gwang-Ho
Lee, Nam-Woo
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-06
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Objective.
The aim of this review is to provide the available evidence on the external use of propolis (EUP) for oral, skin, and genital diseases.
Method.
We searched twelve electronic databases for relevant studies up to June 2016.
Randomized clinical trials (RCTs) were included and analysed.
Results.
Of the 286 articles identified, twelve potentially relevant studies met our inclusion criteria.
A meta-analysis of two studies on recurrent oral aphthae (ROA) indicated that there were no significant differences in total effective rate (TER) for pain disappearance between EUP and placebo groups (RR = 1.96, 95% CI = 0.97–3.98, and P = 0.06 ).
In two studies on skin diseases, the combined treatment of EUP with other interventions revealed significant effects on the duration of treatment or TER.
In one study on genital diseases, EUP showed significant differences in genital herpes outcome measures compared to placebo.
Conclusions.
Our results on the effectiveness of EUP for treating oral, skin, and genital diseases are not conclusive because of the low methodological qualities and small sample sizes.
Further well-designed randomized controlled trials, with high quality and large samples for specific disorders, must be conducted to obtain firm conclusions.
American Psychological Association (APA)
Sung, Soo-Hyun& Choi, Gwang-Ho& Lee, Nam-Woo& Shin, Byung-Cheul. 2017. External Use of Propolis for Oral, Skin, and Genital Diseases: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1154643
Modern Language Association (MLA)
Sung, Soo-Hyun…[et al.]. External Use of Propolis for Oral, Skin, and Genital Diseases: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1154643
American Medical Association (AMA)
Sung, Soo-Hyun& Choi, Gwang-Ho& Lee, Nam-Woo& Shin, Byung-Cheul. External Use of Propolis for Oral, Skin, and Genital Diseases: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1154643
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154643