Electroacupuncture Improved the Function of Myocardial Ischemia Involved in the Hippocampus-Paraventricular Nucleus-Sympathetic Nerve Pathway

Joint Authors

Zhou, Meiqi
Wu, Shengbing
Zhu, Guoqi
Cui, Shuai
Zhou, Yiping
Cao, Jian

Source

Evidence-Based Complementary and Alternative Medicine

Issue

Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-13, 13 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2018-01-01

Country of Publication

Egypt

No. of Pages

13

Main Subjects

Medicine

Abstract EN

We investigated the hippocampus-paraventricular nucleus- (PVN-) sympathetic nerve pathway in electroacupuncture (EA) at the heart meridian for the treatment of myocardial ischemia by observing PVN neuronal discharge, sympathetic nerve discharge, and hemodynamics parameters.

Sprague Dawley (SD) rats were equally divided into four groups: Sham, Model, Model + EA, and Model + EA + Lesion.

The model rat was established by ligating the left anterior descending branch of the coronary artery.

Changes in the sympathetic nerve discharge and hemodynamic parameters were observed.

The Model + EA exhibited a significantly lower discharge frequency of PVN neurons compared with the Model.

The Model + EA + Lesion had a significantly higher discharge frequency compared with the Model + EA.

The total discharge frequency of PVN neurons and interneurons were positively correlated with the sympathetic nerve discharge.

The total discharge frequency of PVN neurons was positively correlated with heart rate (HR) and negatively correlated with mean arterial pressure (MAP) and rate pressure product (RPP).

The discharge frequency of interneurons was positively correlated with HR and negatively correlated with MAP and RPP.

The hippocampus-PVN-sympathetic nerve pathway is involved in electroacupuncture at the heart meridian and interneurons are the key neurons in PVNs.

American Psychological Association (APA)

Cui, Shuai& Zhou, Yiping& Wu, Shengbing& Cao, Jian& Zhu, Guoqi& Zhou, Meiqi. 2018. Electroacupuncture Improved the Function of Myocardial Ischemia Involved in the Hippocampus-Paraventricular Nucleus-Sympathetic Nerve Pathway. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1154691

Modern Language Association (MLA)

Cui, Shuai…[et al.]. Electroacupuncture Improved the Function of Myocardial Ischemia Involved in the Hippocampus-Paraventricular Nucleus-Sympathetic Nerve Pathway. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1154691

American Medical Association (AMA)

Cui, Shuai& Zhou, Yiping& Wu, Shengbing& Cao, Jian& Zhu, Guoqi& Zhou, Meiqi. Electroacupuncture Improved the Function of Myocardial Ischemia Involved in the Hippocampus-Paraventricular Nucleus-Sympathetic Nerve Pathway. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1154691

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1154691