Protective Effect of Tang Wang One Decoction on the Retinal Vessels of Diabetic Rats
Joint Authors
Luo, Dan
Qin, Yali
Jin, Ming
Yang, Shufei
Deng, Tingting
Kou, Xinyun
Yang, Chao
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-03-06
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Objective.
This study aimed to determine the influence of Tang Wang One Decoction (TWOD) on the retinal vessels of diabetic rats.
Methods.
The hemorheology of diabetic rats was observed.
Morphological studies of retinal vessels were conducted using optical microscopy and electron microscopy.
Immunological histochemistry assay was used to measure the expression levels of MMP-9, occludin, and claudin-5.
Results.
Obvious pathological damage was observed in the retinal vessels of diabetic rats.
TWOD positively affected the hemorheology and morphology of retinal vessels.
The decoction also decreased the expression of MMP-9 and increased the expression of occludin and claudin-5.
Conclusions.
The results suggest that the retinal protective effects of TWOD might be related to downregulation of MMP-9 and upregulation of occludin and claudin-5.
American Psychological Association (APA)
Kou, Xinyun& Yang, Shufei& Qin, Yali& Yang, Chao& Deng, Tingting& Luo, Dan…[et al.]. 2017. Protective Effect of Tang Wang One Decoction on the Retinal Vessels of Diabetic Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1154811
Modern Language Association (MLA)
Kou, Xinyun…[et al.]. Protective Effect of Tang Wang One Decoction on the Retinal Vessels of Diabetic Rats. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1154811
American Medical Association (AMA)
Kou, Xinyun& Yang, Shufei& Qin, Yali& Yang, Chao& Deng, Tingting& Luo, Dan…[et al.]. Protective Effect of Tang Wang One Decoction on the Retinal Vessels of Diabetic Rats. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1154811
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154811
