A Review on Worldwide Ephedra History and Story: From Fossils to Natural Products Mass Spectroscopy Characterization and Biopharmacotherapy Potential
Joint Authors
Smaoui, Slim
Mtibaa, Ahlem Chakchouk
Ben Hlima, Hajer
Sellem, Imen
Ennouri, Karim
Fourati, Mariam
Elhadef, Khaoula
Mellouli, Lotfi
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-22, 22 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-04-30
Country of Publication
Egypt
No. of Pages
22
Main Subjects
Abstract EN
Growing worldwide, the genus Ephedra (family Ephedraceae) had a medicinal, ecological, and economic value.
The extraordinary morphological diversity suggests that Ephedra was survivor of an ancient group, and its antiquity is also supported by fossil data.
It has recently been suggested that Ephedra appeared 8–32 million years ago, and a few megafossils document its presence in the Early Cretaceous.
Recently, the high analytical power provided by the new mass spectrometry (MS) instruments is making the characterization of Ephedra metabolites more feasible, such as ephedrine series.
In this regard, the chemical compounds isolated from crude extracts, fractions, and few isolated compounds of Ephedra species were characterized by MS-based techniques (LC-MS, LC-ESI-MS, HPLC-PDA-ESI/MS, LC-DAD-ESI/MSn, LC/Orbitrap MS, etc.).
Moreover, we carry out an exhaustive review of the scientific literature on biomedicine and pharmacotherapy (anticancer, antiproliferative, anti-inflammatory, antidiabetic, antihyperlipidemic, antiarthritic, and anti-influenza activities; proapoptotic and cytotoxic potential; and so on).
Equally, antimicrobial and antioxidant activities were discussed.
This review is focused on all these topics, along with current studies published in the last 5 years (2015–2019) providing in-depth information for readers.
American Psychological Association (APA)
Elhadef, Khaoula& Smaoui, Slim& Fourati, Mariam& Ben Hlima, Hajer& Mtibaa, Ahlem Chakchouk& Sellem, Imen…[et al.]. 2020. A Review on Worldwide Ephedra History and Story: From Fossils to Natural Products Mass Spectroscopy Characterization and Biopharmacotherapy Potential. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-22.
https://search.emarefa.net/detail/BIM-1154864
Modern Language Association (MLA)
Elhadef, Khaoula…[et al.]. A Review on Worldwide Ephedra History and Story: From Fossils to Natural Products Mass Spectroscopy Characterization and Biopharmacotherapy Potential. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-22.
https://search.emarefa.net/detail/BIM-1154864
American Medical Association (AMA)
Elhadef, Khaoula& Smaoui, Slim& Fourati, Mariam& Ben Hlima, Hajer& Mtibaa, Ahlem Chakchouk& Sellem, Imen…[et al.]. A Review on Worldwide Ephedra History and Story: From Fossils to Natural Products Mass Spectroscopy Characterization and Biopharmacotherapy Potential. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-22.
https://search.emarefa.net/detail/BIM-1154864
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154864