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Chinese Classical Formula Sijunzi Decoction and Chronic Atrophic Gastritis: Evidence for Treatment Approach?
Joint Authors
Gan, Danan
Xu, Aili
Du, Hongbo
Ye, Yong’an
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-24
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objective.
This aim is to evaluate the effect of Sijunzi decoction (SJZD) treating chronic atrophic gastritis (CAG).
Methods.
We performed searches in seven databases.
The randomized controlled trials (RCTs) comparing SJZD with standard medical care or inactive intervention for CAG were enrolled.
Combined therapy of SJZD plus conventional therapies compared with conventional therapies alone was also retrieved.
The primary outcome included the incidence of gastric cancer and the improvement of atrophy, intestinal metaplasia, and dysplasia based on the gastroscopy and pathology.
The secondary outcomes were Helicobacter pylori clearance rate, quality of life, and adverse event/adverse drug reaction.
Results.
Six RCTs met the inclusion criteria.
The research quality was low in the trials.
For the overall effect rate, pooled analysis from 4 trials showed that modified SJZD plus conventional medications exhibited a significant improvement (OR = 4.86; 95% CI: 2.80 to 8.44; P < 0.00001) and without significant heterogeneity compared with the conventional medications alone.
None reported the adverse effect.
Conclusions.
Modified SJZD combined with conventional western medicines appears to have benefits for CAG.
Due to the limited number and methodological flaw, the beneficial and harmful effects of SJZD for CAG could not be identified.
More high-quality clinical trials are needed to confirm the results.
American Psychological Association (APA)
Gan, Danan& Xu, Aili& Du, Hongbo& Ye, Yong’an. 2017. Chinese Classical Formula Sijunzi Decoction and Chronic Atrophic Gastritis: Evidence for Treatment Approach?. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1154878
Modern Language Association (MLA)
Gan, Danan…[et al.]. Chinese Classical Formula Sijunzi Decoction and Chronic Atrophic Gastritis: Evidence for Treatment Approach?. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1154878
American Medical Association (AMA)
Gan, Danan& Xu, Aili& Du, Hongbo& Ye, Yong’an. Chinese Classical Formula Sijunzi Decoction and Chronic Atrophic Gastritis: Evidence for Treatment Approach?. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1154878
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154878