![](/images/graphics-bg.png)
Number 2 Feibi Recipe Reduces PM2.5-Induced Lung Injury in Rats
Joint Authors
Liu, Zhaoheng
Wang, Wei
Cao, Fang
Liu, Shuo
Zou, Xinxin
Li, Guodong
Yang, Haojie
Jiao, Yang
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-09
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Air pollution is the main cause of respiratory diseases.
Fine particulates with the diameter below 2.5 μm can get into the alveoli and then enter the blood circulation through the lung tissue ventilation function and cause multiple systemic diseases especially the respiratory diseases.
This study investigated the pathological mechanism of the lungs injury in rats induced by PM2.5 and the effect and mechanism of the Chinese herbal medicine number 2 Feibi Recipe (number 2 FBR) on lungs injury.
In this experiment, Wistar rats were used.
Lungs injury was induced by PM2.5.
Number 2 FBR was used to treat the rats.
The result showed that number 2 FBR could improve the lung injury in the rats.
Meanwhile, it significantly reduced pathological response and inflammatory mediators including interleukin-6 (IL-6), interleukin-13 (IL-13), interleukin-17 (IL17), monocyte chemotactic protein-1 (MCP-1), and transforming growth factor-α (TNF-α) and upregulated glutathione peroxidase (GSH-Px) in the PM2.5 induced lung injury in the rats.
Collectively, number 2 FBR appears to attenuate the lungs injury in rats induced by PM2.5.
American Psychological Association (APA)
Liu, Zhaoheng& Wang, Wei& Cao, Fang& Liu, Shuo& Zou, Xinxin& Li, Guodong…[et al.]. 2018. Number 2 Feibi Recipe Reduces PM2.5-Induced Lung Injury in Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1154942
Modern Language Association (MLA)
Liu, Zhaoheng…[et al.]. Number 2 Feibi Recipe Reduces PM2.5-Induced Lung Injury in Rats. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1154942
American Medical Association (AMA)
Liu, Zhaoheng& Wang, Wei& Cao, Fang& Liu, Shuo& Zou, Xinxin& Li, Guodong…[et al.]. Number 2 Feibi Recipe Reduces PM2.5-Induced Lung Injury in Rats. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1154942
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154942