Biological Activities of Four Adaptogenic Plant Extracts and Their Active Substances on a Rotifer Model
Joint Authors
Csupor, Dezső
Mácsai, Lilla
Datki, Zsolt L.
Horváth, Attila
Zomborszki, Zoltán P.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-10-14
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Rotifers have been widely used as well-characterized models of aging, since their multiorgan character makes them suitable as in vivo toxicological and lifespan models.
Here we report the assessment of four adaptogenic plants and their extracts for the first time in this model.
The effects on rotifer viability of extracts and characteristic active markers of Panax ginseng, Withania somnifera, Leuzea carthamoides, and Rhodiola rosea were tested in vivo.
The crude extracts were nontoxic to Philodina acuticornis bdelloid rotifers; however, the pure substances of the plants influenced negatively the viability.
Ginsenoside Rb1 and secondary metabolites of Withania somnifera exerted deleterious effect on the animals.
The aglycone tyrosol and cinnamyl alcohol (from Rhodiola rosea) were more toxic than their glycosides salidroside and rosavin.
Although the 20-OH-ecdysone and ajugasterone C (from Leuzea carthamoides) are chemically very similar, the latter was less toxic.
American Psychological Association (APA)
Mácsai, Lilla& Datki, Zsolt L.& Csupor, Dezső& Horváth, Attila& Zomborszki, Zoltán P.. 2018. Biological Activities of Four Adaptogenic Plant Extracts and Their Active Substances on a Rotifer Model. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1154948
Modern Language Association (MLA)
Mácsai, Lilla…[et al.]. Biological Activities of Four Adaptogenic Plant Extracts and Their Active Substances on a Rotifer Model. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1154948
American Medical Association (AMA)
Mácsai, Lilla& Datki, Zsolt L.& Csupor, Dezső& Horváth, Attila& Zomborszki, Zoltán P.. Biological Activities of Four Adaptogenic Plant Extracts and Their Active Substances on a Rotifer Model. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1154948
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154948