Diagnosing Celiac Disease: Towards Wide-Scale Screening and Serology-Based Criteria?
Joint Authors
Popp, Alina
Kivelä, Laura
Fuchs, Valma
Kurppa, Kalle
Source
Gastroenterology Research and Practice
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-08-06
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Celiac disease is one of the most common food-related chronic disorders in children.
Unfortunately, this multifaceted disease is challenging to recognize and remains markedly underdiagnosed.
Screening of either known at-risk groups or even the whole population could increase the suboptimal diagnostic yield substantially.
Many recent guidelines recommend screening of at least selected risk groups, but more wide-scale screening remains controversial.
The increasing prevalence of celiac disease and the development of autoantibody assays have also led to a gradual shift in the diagnostics towards less invasive serology-based criteria in a subgroup of symptomatic children.
The main open questions concern whether these criteria are applicable to all countries and clinical settings, as well as to adult patients.
On the other hand, widening screening and the mistaken practice of initiating a gluten-free diet before the appropriate exclusion of celiac disease increase the number of borderline seropositive cases, which may also challenge the classical histopathological diagnostics.
Sophisticated diagnostic methods and a deeper understanding of the natural history of early developing celiac disease may prove useful in these circumstances.
American Psychological Association (APA)
Popp, Alina& Kivelä, Laura& Fuchs, Valma& Kurppa, Kalle. 2019. Diagnosing Celiac Disease: Towards Wide-Scale Screening and Serology-Based Criteria?. Gastroenterology Research and Practice،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1154950
Modern Language Association (MLA)
Popp, Alina…[et al.]. Diagnosing Celiac Disease: Towards Wide-Scale Screening and Serology-Based Criteria?. Gastroenterology Research and Practice No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1154950
American Medical Association (AMA)
Popp, Alina& Kivelä, Laura& Fuchs, Valma& Kurppa, Kalle. Diagnosing Celiac Disease: Towards Wide-Scale Screening and Serology-Based Criteria?. Gastroenterology Research and Practice. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1154950
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1154950