Determination of the Wound Healing Potentials of Medicinal Plants Historically Used in Ghana
Joint Authors
Freiesleben, Sara H.
Soelberg, Jens
Nyberg, Nils T.
Jäger, Anna K.
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-23
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
The present study was carried out to investigate the wound healing potentials of 17 medicinal plants historically used in Ghana for wound healing.
Warm and cold water extracts were prepared from the 17 dried plant species and tested in vitro in the scratch assay with NIH 3T3 fibroblasts from mice.
The wound healing scratch assay was used to evaluate the effect of the plants on cell proliferation and/or migration in vitro, as a test for potential wound healing properties.
After 21 hours of incubation increased proliferation and/or migration of fibroblasts in the scratch assay was obtained for 5 out of the 17 plant species.
HPLC separation of the most active plant extract, which was a warm water extract of Philenoptera cyanescens, revealed the wound healing activity to be attributed to rutin and a triglycoside of quercetin.
The present study suggests that Allophylus spicatus, Philenoptera cyanescens, Melanthera scandens, Ocimum gratissimum, and Jasminum dichotomum have wound healing activity in vitro.
American Psychological Association (APA)
Freiesleben, Sara H.& Soelberg, Jens& Nyberg, Nils T.& Jäger, Anna K.. 2017. Determination of the Wound Healing Potentials of Medicinal Plants Historically Used in Ghana. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1155016
Modern Language Association (MLA)
Freiesleben, Sara H.…[et al.]. Determination of the Wound Healing Potentials of Medicinal Plants Historically Used in Ghana. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1155016
American Medical Association (AMA)
Freiesleben, Sara H.& Soelberg, Jens& Nyberg, Nils T.& Jäger, Anna K.. Determination of the Wound Healing Potentials of Medicinal Plants Historically Used in Ghana. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1155016
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155016