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Efficacy and Safety of Modified Banxia Xiexin Decoction (Pinellia Decoction for Draining the Heart) for Gastroesophageal Reflux Disease in Adults: A Systematic Review and Meta-Analysis
Joint Authors
Dai, Yunkai
Zhang, Yunzhan
Li, Danyan
Ye, Jintong
Chen, Weijing
Hu, Ling
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-17, 17 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-19
Country of Publication
Egypt
No. of Pages
17
Main Subjects
Abstract EN
Modified Banxia Xiexin decoction (MBXD) is a classical Chinese herbal formula in treating gastroesophageal reflux disease (GERD) for long time, but the efficacy of it is still controversial.
This study is to evaluate the efficacy and safety of MBXD for the treatment of GERD in adults.
The search strategy was carried out for publications in seven electronic databases.
RevMan software version 5.3 and the Cochrane Collaboration’s risk of bias tool were performed for this review.
Twelve RCTs were included for the analysis.
The results of overall clinical efficacy and efficacy under gastroscope demonstrated that MBXD was superior to conventional western medicine.
Meanwhile, the results of subgroup analysis showed clinical heterogeneity between the two groups.
However, there was no statistically significant difference in acid regurgitation between the two groups.
But in the improvement of heartburn and sternalgia, the results showed statistically significant differences for the comparison between two groups.
In addition, the adverse reactions of the experiment groups were not different from those of the control groups.
This systematic review indicates that MBXD may have potential effects on the treatment of patients with GERD.
But because the evidence of methodological quality and sample sizes is weak, further standardized researches are required.
American Psychological Association (APA)
Dai, Yunkai& Zhang, Yunzhan& Li, Danyan& Ye, Jintong& Chen, Weijing& Hu, Ling. 2017. Efficacy and Safety of Modified Banxia Xiexin Decoction (Pinellia Decoction for Draining the Heart) for Gastroesophageal Reflux Disease in Adults: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2017, no. 2017, pp.1-17.
https://search.emarefa.net/detail/BIM-1155034
Modern Language Association (MLA)
Dai, Yunkai…[et al.]. Efficacy and Safety of Modified Banxia Xiexin Decoction (Pinellia Decoction for Draining the Heart) for Gastroesophageal Reflux Disease in Adults: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2017 (2017), pp.1-17.
https://search.emarefa.net/detail/BIM-1155034
American Medical Association (AMA)
Dai, Yunkai& Zhang, Yunzhan& Li, Danyan& Ye, Jintong& Chen, Weijing& Hu, Ling. Efficacy and Safety of Modified Banxia Xiexin Decoction (Pinellia Decoction for Draining the Heart) for Gastroesophageal Reflux Disease in Adults: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2017. Vol. 2017, no. 2017, pp.1-17.
https://search.emarefa.net/detail/BIM-1155034
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155034