The Prebiotic-Like Effects of Coprinus comatus Polysaccharides on Gut Microbiota in Normal Mice and Those with Acute Alcoholic Liver Injury: A Comparative Study
Joint Authors
Li, Weidong
Sun, Min
Qi, Dongmei
Cai, Xiaoqing
Wang, Yongxia
Liang, Yuting
Zhang, Yongqing
Han, Chunchao
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-29
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
This study aims to investigate the prebiotic-like effects of Coprinus comatus polysaccharides (CCP) on gut microbiota.
Mice were divided into four groups: normal group (NG), alcohol group (AG), polysaccharides group (PG), and alcohol + polysaccharides group (APG).
The gut microbiota structure of feces was analyzed by determining the V3-V4 region sequence in 16S rDNA.
The results showed CCP could increase the diversity of gut microbiota.
Compared with NG, PG had a significantly higher relative abundance of Firmicutes and Lactobacillaceae and a lower abundance of Rikenellaceae.
These changes in gut microbiota result in positive effects on gut due to a series of prebiotic-like effects of CCP.
At the same time, CCP could improve some adverse changes in gut microbiota caused by acute alcohol intake, such as the increased proportion of Firmicutes, Bacteroidetes, Muribaculaceae, and Lachnospiraceae and the decreased proportion of Rikenellaceae.
In conclusion, the CCP has certain prebiotic effects not only on normal mice but also on mice with acute alcoholic liver injury.
American Psychological Association (APA)
Li, Weidong& Wang, Yongxia& Sun, Min& Liang, Yuting& Cai, Xiaoqing& Qi, Dongmei…[et al.]. 2020. The Prebiotic-Like Effects of Coprinus comatus Polysaccharides on Gut Microbiota in Normal Mice and Those with Acute Alcoholic Liver Injury: A Comparative Study. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1155043
Modern Language Association (MLA)
Li, Weidong…[et al.]. The Prebiotic-Like Effects of Coprinus comatus Polysaccharides on Gut Microbiota in Normal Mice and Those with Acute Alcoholic Liver Injury: A Comparative Study. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1155043
American Medical Association (AMA)
Li, Weidong& Wang, Yongxia& Sun, Min& Liang, Yuting& Cai, Xiaoqing& Qi, Dongmei…[et al.]. The Prebiotic-Like Effects of Coprinus comatus Polysaccharides on Gut Microbiota in Normal Mice and Those with Acute Alcoholic Liver Injury: A Comparative Study. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1155043
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155043