The Effect of Pluchea indica (L.) Less. Tea on Adipogenesis in 3T3-L1 Adipocytes and Lipase Activity
Joint Authors
Eumkeb, Griangsak
Sirichaiwetchakoon, Kittipot
Lowe, Gordon Matthew
Thumanu, Kanjana
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-12
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Obesity and hyperlipidemia are a major problem in the world.
Pluchea indica (L.) Less.
tea (PIT) is a beverage that has various indications.
This study focused on the effect of the PIT on inhibiting adipogenesis of 3T3-L1 cells and pancreatic lipase enzyme activity.
The viability of 3T3-L1 cells was not significantly decreased after exposure to 200 to 1000 μg mL−1 PIT compared to controls (p>0.05).
The PIT at 750 to 1000 μg mL−1 exhibited a significantly reduced lipid accumulation compared to the control (p<0.05).
The inhibitory effects of the PIT at 250 to 1000 μg mL−1 on lipase activity were significantly increased compared to control (p<0.05).
The FTIR results showed that the integrated areas of lipids, proteins, nucleic acids, glycogen, and carbohydrates of the PIT-treated 3T3-L1 adipocytes were significantly lower than the untreated 3T3-L1 adipocytes (p<0.05).
These findings may indicate that the PIT is not only capable of inhibiting lipids and carbohydrate accumulation in adipocytes but also has a potential to inhibit pancreatic lipase activity.
So, the PIT may be further developed to the novel lipid-lowering herbal supplement for the management of overweight or obesity.
American Psychological Association (APA)
Sirichaiwetchakoon, Kittipot& Lowe, Gordon Matthew& Thumanu, Kanjana& Eumkeb, Griangsak. 2018. The Effect of Pluchea indica (L.) Less. Tea on Adipogenesis in 3T3-L1 Adipocytes and Lipase Activity. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1155085
Modern Language Association (MLA)
Sirichaiwetchakoon, Kittipot…[et al.]. The Effect of Pluchea indica (L.) Less. Tea on Adipogenesis in 3T3-L1 Adipocytes and Lipase Activity. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1155085
American Medical Association (AMA)
Sirichaiwetchakoon, Kittipot& Lowe, Gordon Matthew& Thumanu, Kanjana& Eumkeb, Griangsak. The Effect of Pluchea indica (L.) Less. Tea on Adipogenesis in 3T3-L1 Adipocytes and Lipase Activity. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1155085
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155085