Changes in the Management of Patients with Crohn’s Disease Based on Magnetic Resonance Enterography Patterns
Joint Authors
Chinem, Evelyn Sayuri S.
Esberard, Barbara C.
Moreira, Andre da L.
Barbassa, Tatiana G.
da Cunha, Guilherme M.
Carneiro, Antonio Jose de V.
Carvalho, Ana Teresa P.
de Souza, Heitor S.
Source
Gastroenterology Research and Practice
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-12-17
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Background and Aims.
Magnetic resonance enterography (MRE) has become an important modality of radiological imaging in the evaluation of Crohn’s disease (CD).
The aim of this study was to investigate the impact of MRE in the assessment of disease activity and abdominal complications and in the making of therapeutic decisions for patients with CD.
Methods.
In a cross-sectional retrospective study, we selected 74 patients with CD who underwent MRE and ileocolonoscopy with an interval between the two exams of up to 30 days between January 2011 and December 2017.
We assessed the parameters of the images obtained by MRE and investigated the agreement with the level of disease activity and complications determined by a clinical evaluation, inflammatory biomarkers, and endoscopy, as well as the resulting changes in medical and surgical management.
Results.
Changes in medical management were detected in 41.9% of patients.
Significant changes in medical decisions were observed in individuals with a purely penetrating (P=.012) or a mixed (P=.024) MRE pattern.
Patients with normal MRE patterns had a correlation with unchanged medical decisions (P=.001).
There were statistically significant agreements between the absence of inflammatory criteria on MRE and remission according to the Harvey and Bradshaw index (HBI) (P=.037), the presence of inflammatory criteria on MRE and positive results for calprotectin (P=.005), and penetrating criteria on MRE and the scoring endoscopic system for Crohn’s disease (SES-CD), indicating active disease (P=.048).
Finally, there was significant agreement between the presence of fibrostenotic criteria and a long disease duration (P=.027).
Conclusion.
MRE discloses disease activity and complications not apparent with other modalities and results in changes in therapeutic decisions.
In addition to being used for diagnosis, MRE should be routinely used in the follow-up of CD patients.
American Psychological Association (APA)
Chinem, Evelyn Sayuri S.& Esberard, Barbara C.& Moreira, Andre da L.& Barbassa, Tatiana G.& da Cunha, Guilherme M.& Carneiro, Antonio Jose de V.…[et al.]. 2019. Changes in the Management of Patients with Crohn’s Disease Based on Magnetic Resonance Enterography Patterns. Gastroenterology Research and Practice،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1155092
Modern Language Association (MLA)
Chinem, Evelyn Sayuri S.…[et al.]. Changes in the Management of Patients with Crohn’s Disease Based on Magnetic Resonance Enterography Patterns. Gastroenterology Research and Practice No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1155092
American Medical Association (AMA)
Chinem, Evelyn Sayuri S.& Esberard, Barbara C.& Moreira, Andre da L.& Barbassa, Tatiana G.& da Cunha, Guilherme M.& Carneiro, Antonio Jose de V.…[et al.]. Changes in the Management of Patients with Crohn’s Disease Based on Magnetic Resonance Enterography Patterns. Gastroenterology Research and Practice. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1155092
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155092