Is There a Role of Using a Rapid Finger Prick Antibody Test in Screening for Celiac Disease in Children?
Joint Authors
Baraba Dekanić, Kristina
Butorac Ahel, Ivona
Ružman, Lucija
Dolinšek, Jasmina
Dolinšek, Jernej
Palčevski, Goran
Source
Gastroenterology Research and Practice
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-10-07
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Introduction.
Celiac disease (CD) is an autoimmune disease triggered by gluten in genetically predisposed individuals.
Despite the increasing prevalence of CD, many patients remain undiagnosed.
Standard serology tests are expensive and invasive, so several point-of-care tests (POC) for CD have been developed.
We aimed to determine the prevalence of CD in first-grade pupils in Primorje-Gorski Kotar County, Croatia, using a POC test.
Methods.
A Biocard celiac test that detects IgA antibodies to tissue transglutaminase in whole blood was used to screen for celiac disease in healthy first-grade children born in 2011 and 2012 who consumed gluten without restrictions.
Results.
1478 children were tested, and none of them were tested positive with a rapid test.
In 10 children (0,6%), IgA deficiency has been suspected; only 4 of them agreed to be tested further for total IgA, anti-tTG, and anti-DGP antibodies.
IgA deficiency was confirmed in 3 patients, and in all 4 children, CD has been excluded.
Conclusion.
Our results have not confirmed the usefulness of the POC test in screening the general population of first-grade schoolchildren.
Further research is needed to establish the true epidemiology of CD in Primorje-Gorski Kotar County and to confirm the value of the rapid test in comparison with standard antibody CD testing.
American Psychological Association (APA)
Baraba Dekanić, Kristina& Butorac Ahel, Ivona& Ružman, Lucija& Dolinšek, Jasmina& Dolinšek, Jernej& Palčevski, Goran. 2019. Is There a Role of Using a Rapid Finger Prick Antibody Test in Screening for Celiac Disease in Children?. Gastroenterology Research and Practice،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1155200
Modern Language Association (MLA)
Baraba Dekanić, Kristina…[et al.]. Is There a Role of Using a Rapid Finger Prick Antibody Test in Screening for Celiac Disease in Children?. Gastroenterology Research and Practice No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1155200
American Medical Association (AMA)
Baraba Dekanić, Kristina& Butorac Ahel, Ivona& Ružman, Lucija& Dolinšek, Jasmina& Dolinšek, Jernej& Palčevski, Goran. Is There a Role of Using a Rapid Finger Prick Antibody Test in Screening for Celiac Disease in Children?. Gastroenterology Research and Practice. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1155200
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155200