Endoscopic Ultrasound Findings in Patients Diagnosed with Exocrine Pancreatic Insufficiency by Low Fecal Elastase-1
Joint Authors
Othman, Mohamed
Shobassy, Mazen
Husainat, Nedaa
Tabash, Abdalaziz
Patel, Kalpesh
El-Serag, Hashem B.
Source
Gastroenterology Research and Practice
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-5, 5 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-08-14
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Abstract EN
Background and Aims.
Fecal elastase-1 (FE-1) as a screening test for exocrine pancreatic insufficiency (EPI) is gaining popularity in clinical practice.
The role of imaging in patients with FE-1-related suspicion of EPI remains unclear.
The aim of this study was to characterize endoscopic ultrasound (EUS) findings for patients with low FE-1.
Methods.
A retrospective cross-sectional study was performed in 40 patients who had low FE-1 and underwent EUS to evaluate the pancreas.
We obtained data on demographic and lifestyle factors, EUS findings, and histopathology results.
We compared these variables between patients with FE‐1<100 mcg/g vs.
100-200 mcg/g.
Results.
Most patients (82.5%) established one or more new diagnoses from EUS.
Diagnoses included: definitive chronic pancreatitis (n=29, 72.5%), fatty pancreas (n=9, 22.5%), and pancreatic solid mass or cyst (n=9, 22.5%).
Half (n=4) of the solid or cystic lesions were neoplastic.
All patients with a solid pancreatic mass also had concurrent chronic pancreatitis.
There were no significant differences in EUS findings or demographic or lifestyle factors between groups with FE‐1<100 mcg/g vs.
100-200 mcg/g.
Conclusion.
Chronic pancreatitis is the most common EUS finding in patients with low FE-1 levels.
EUS appears helpful in determining the cause of EPI in most patients with low FE-1 and may detect unsuspected pancreatic neoplasia.
American Psychological Association (APA)
Shobassy, Mazen& Husainat, Nedaa& Tabash, Abdalaziz& Patel, Kalpesh& El-Serag, Hashem B.& Othman, Mohamed. 2019. Endoscopic Ultrasound Findings in Patients Diagnosed with Exocrine Pancreatic Insufficiency by Low Fecal Elastase-1. Gastroenterology Research and Practice،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1155241
Modern Language Association (MLA)
Shobassy, Mazen…[et al.]. Endoscopic Ultrasound Findings in Patients Diagnosed with Exocrine Pancreatic Insufficiency by Low Fecal Elastase-1. Gastroenterology Research and Practice No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1155241
American Medical Association (AMA)
Shobassy, Mazen& Husainat, Nedaa& Tabash, Abdalaziz& Patel, Kalpesh& El-Serag, Hashem B.& Othman, Mohamed. Endoscopic Ultrasound Findings in Patients Diagnosed with Exocrine Pancreatic Insufficiency by Low Fecal Elastase-1. Gastroenterology Research and Practice. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1155241
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155241