Protocol of the Development of a Core Outcome Set for Ischemic Stroke in Clinical Trials of Chinese Medicine
Joint Authors
Liu, Shaonan
Cai, Yefeng
Xie, Qianwen
Deng, Xueyi
Xiao, Jingmin
Chen, Xueyin
He, Yihan
Yang, Lihong
Lai, Jiaqi
Sun, Jingbo
Guo, Xinfeng
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-10-05
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Ischemic stroke (IS) seriously impacts the quality of life of survivors.
Chinese medicine (CM) has been developed for more than 2000 years and plays a key role in the treatment of ischemic stroke.
Many Chinese medicine clinical trials have been conducted; however, the heterogeneity of outcome measurements and reporting limits implications of the findings in clinical practice and health policy development.
Therefore, it is important to develop a core outcome set (COS) that should be used and reported in trials for ischemic stroke treated by Chinese medicine.
This protocol describes the process of developing the IS-CM-COS.
Methods and Analysis.
The development of the COS will involve the following four steps: (1) A list of outcomes reported in the registered and published Chinese medicine trials of ischemic stroke will be extracted by conducting a systematic literature review.
(2) An additional outcome list will be collected by semistructured interview to patients with ischemic stroke.
(3) A two-round Delphi survey will be performed to prioritize and condense the outcomes.
(4) In the consensus meeting, a final recommended COS will be developed.
Discussion.
The COS could improve the reliability and consistency of outcome reporting.
We hope that this IS-CM-COS will be used in the future Chinese medicine trials for the treatment of ischemic stroke and improve research quality.
Trial Registration.
This study was registered with the Core Outcome Measures in Effectiveness Trials Initiative (http://www.comet-initiative.org/studies/details/1282).
American Psychological Association (APA)
Xie, Qianwen& Deng, Xueyi& Xiao, Jingmin& Chen, Xueyin& He, Yihan& Yang, Lihong…[et al.]. 2020. Protocol of the Development of a Core Outcome Set for Ischemic Stroke in Clinical Trials of Chinese Medicine. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1155325
Modern Language Association (MLA)
Xie, Qianwen…[et al.]. Protocol of the Development of a Core Outcome Set for Ischemic Stroke in Clinical Trials of Chinese Medicine. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1155325
American Medical Association (AMA)
Xie, Qianwen& Deng, Xueyi& Xiao, Jingmin& Chen, Xueyin& He, Yihan& Yang, Lihong…[et al.]. Protocol of the Development of a Core Outcome Set for Ischemic Stroke in Clinical Trials of Chinese Medicine. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1155325
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155325