Impact of Helicobacter pylori Infection on Gastric Variceal Bleeding among Patients with Liver Cirrhosis
Joint Authors
Abd-Elsalam, Sherief
Elsebaey, Mohamed A.
Tawfik, Mohamed A.
Elshweikh, Samah A.
Negm, Manal Saad
Elnaggar, Mohammed H.
Alghazaly, Ghada Mahmoud
Source
Gastroenterology Research and Practice
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-10
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background and Aims.
Currently, it is well known that Helicobacter pylori- (H.
pylori-) related peptic ulcer is one of the main causes of nonvariceal bleeding in cirrhotic patients.
However, there is a lack of data to identify the exact effect of H.
pylori infection on variceal bleeding.
This study was conducted to identify the impact of H.
pylori infection on gastric variceal bleeding in cirrhotic patients.
Patients and Methods.
76 cirrhotic patients with gastric varices were included in this prospective study and divided into 2 groups: nonbleeding gastric varices (32 patients) and bleeding gastric varices (44 patients).
The fasting serum gastrin level was measured.
Mucosal biopsies from the gastric body and antrum were examined to determine the patterns of gastritis and the presence of H.
pylori.
Results.
The frequency of H.
pylori infection in the studied patients was 59.2%.
There were significant differences between both groups regarding liver decompensation (P=0.001), red color sign over gastric varices (P=0.0011), prevalence of H.
pylori infection (P=0.0049), histological patterns of gastritis (P=0.0069), and serum gastrin level (P=0.0200).
By multivariate analysis, Child C cirrhosis, red color sign over gastric varices, and H.
pylori-induced follicular gastritis were independent risk factors for bleeding from gastric varices.
Conclusion.
H.
pylori-induced follicular gastritis is considered as an additional risk factor for bleeding from gastric varices.
American Psychological Association (APA)
Elsebaey, Mohamed A.& Tawfik, Mohamed A.& Elshweikh, Samah A.& Negm, Manal Saad& Elnaggar, Mohammed H.& Alghazaly, Ghada Mahmoud…[et al.]. 2019. Impact of Helicobacter pylori Infection on Gastric Variceal Bleeding among Patients with Liver Cirrhosis. Gastroenterology Research and Practice،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1155339
Modern Language Association (MLA)
Elsebaey, Mohamed A.…[et al.]. Impact of Helicobacter pylori Infection on Gastric Variceal Bleeding among Patients with Liver Cirrhosis. Gastroenterology Research and Practice No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1155339
American Medical Association (AMA)
Elsebaey, Mohamed A.& Tawfik, Mohamed A.& Elshweikh, Samah A.& Negm, Manal Saad& Elnaggar, Mohammed H.& Alghazaly, Ghada Mahmoud…[et al.]. Impact of Helicobacter pylori Infection on Gastric Variceal Bleeding among Patients with Liver Cirrhosis. Gastroenterology Research and Practice. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1155339
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1155339